TY - JOUR
T1 - Metered dose inhaler
T2 - Past, present, and future
AU - Vaswani, Surender K.
AU - Creticos, Peter S.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 1998/1
Y1 - 1998/1
N2 - Background: The metered dose inhaler (MDI) to treat respiratory diseases was introduced many years ago. Due to the recently proposed ban on chlorofluorocarbon (Freon) production, the survival of the conventional MDI is uncertain. It is therefore incumbent on asthma caretakers to familiarize themselves with newer versions of the inhaler. Objective: To review the different modalities of aerosolized treatment employed in the management of asthma. This article is specifically focused on issues related to MDIs, the propellants, and the modifications since its introduction. Data Source: The MEDLINE database was used to review MDI related literature in the English language. Conclusion: Dry powder inhalers (especially the multi-dose type) and Freon-free pressurized MDIs appear promising and probably will replace conventional freonpropelled pressurized MDIs when Freon is no longer available.
AB - Background: The metered dose inhaler (MDI) to treat respiratory diseases was introduced many years ago. Due to the recently proposed ban on chlorofluorocarbon (Freon) production, the survival of the conventional MDI is uncertain. It is therefore incumbent on asthma caretakers to familiarize themselves with newer versions of the inhaler. Objective: To review the different modalities of aerosolized treatment employed in the management of asthma. This article is specifically focused on issues related to MDIs, the propellants, and the modifications since its introduction. Data Source: The MEDLINE database was used to review MDI related literature in the English language. Conclusion: Dry powder inhalers (especially the multi-dose type) and Freon-free pressurized MDIs appear promising and probably will replace conventional freonpropelled pressurized MDIs when Freon is no longer available.
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U2 - 10.1016/s1081-1206(10)62933-x
DO - 10.1016/s1081-1206(10)62933-x
M3 - Review article
C2 - 9475561
AN - SCOPUS:0031933515
SN - 1081-1206
VL - 80
SP - 11
EP - 20
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
IS - 1
ER -