Metered dose inhaler: Past, present, and future

Surender K. Vaswani, Peter S. Creticos

Research output: Contribution to journalReview articlepeer-review


Background: The metered dose inhaler (MDI) to treat respiratory diseases was introduced many years ago. Due to the recently proposed ban on chlorofluorocarbon (Freon) production, the survival of the conventional MDI is uncertain. It is therefore incumbent on asthma caretakers to familiarize themselves with newer versions of the inhaler. Objective: To review the different modalities of aerosolized treatment employed in the management of asthma. This article is specifically focused on issues related to MDIs, the propellants, and the modifications since its introduction. Data Source: The MEDLINE database was used to review MDI related literature in the English language. Conclusion: Dry powder inhalers (especially the multi-dose type) and Freon-free pressurized MDIs appear promising and probably will replace conventional freonpropelled pressurized MDIs when Freon is no longer available.

Original languageEnglish (US)
Pages (from-to)11-20
Number of pages10
JournalAnnals of Allergy, Asthma and Immunology
Issue number1
StatePublished - Jan 1998

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine

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