TY - JOUR
T1 - Metastatic breast carcinoma presenting as a large pulmonary embolus
T2 - Case report and review of the literature
AU - Geschwind, Jean Francois H.
AU - Dagli, Mandeep S.
AU - Vogel-Claussen, Jens
AU - Seifter, Eric
AU - Huncharek, Michael S.
PY - 2003/2
Y1 - 2003/2
N2 - Involvement of the pulmonary vasculature by carcinoma of the breast typically occurs in the form of microscopic tumor emboli involving the small arteries, arterioles, or capillaries. Obstruction of a large pulmonary artery by a tumor embolus has not been reported. We describe a patient with a history of breast carcinoma diagnosed 5 years previously who sought treatment for dyspnea and a large mass in the right pulmonary artery suggestive of a pulmonary embolus. After failure of both systemic and intraarterial thrombolytic therapy, a biopsy of the mass was obtained, which revealed adenocarcinoma of the breast. Systemic chemotherapy with doxorubicin and cyclophosphamide was initiated and resulted in the complete resolution of her symptoms.
AB - Involvement of the pulmonary vasculature by carcinoma of the breast typically occurs in the form of microscopic tumor emboli involving the small arteries, arterioles, or capillaries. Obstruction of a large pulmonary artery by a tumor embolus has not been reported. We describe a patient with a history of breast carcinoma diagnosed 5 years previously who sought treatment for dyspnea and a large mass in the right pulmonary artery suggestive of a pulmonary embolus. After failure of both systemic and intraarterial thrombolytic therapy, a biopsy of the mass was obtained, which revealed adenocarcinoma of the breast. Systemic chemotherapy with doxorubicin and cyclophosphamide was initiated and resulted in the complete resolution of her symptoms.
KW - Breast cancer
KW - Endovascular biopsy
KW - Metastases
KW - Pulmonary embolus
KW - Tumor embolus
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U2 - 10.1097/00000421-200302000-00017
DO - 10.1097/00000421-200302000-00017
M3 - Article
C2 - 12576931
AN - SCOPUS:0037318913
SN - 0277-3732
VL - 26
SP - 89
EP - 91
JO - American Journal of Clinical Oncology: Cancer Clinical Trials
JF - American Journal of Clinical Oncology: Cancer Clinical Trials
IS - 1
ER -