Metastatic breast cancer: Preliminary results with oral hormonal therapy

Joseph C. Allegra; J. Bertino; P. Bonomi; P. Byrne; John Carpenter; R. Catalano; R. Creech; B. Dana; H. Durivage; L. Einhorn; D. Ettinger; F. A. Greco; E. Greenwald; I. Henderson; F. Holmes; Barry Kinzbrunner; S. Luedke; H. Muss; N. Nimeh; R. Talley; G. Wampler; Neal Weinreb; J. Weisberg; R. Wheeler; P. Wiernik

Metastatic breast cancer: Preliminary results with oral hormonal therapy

Joseph C. Allegra, J. Bertino, P. Bonomi, P. Byrne, John Carpenter, R. Catalano, R. Creech, B. Dana, H. Durivage, L. Einhorn, D. Ettinger, F. A. Greco, E. Greenwald, I. Henderson, F. Holmes, Barry Kinzbrunner, S. Luedke, H. Muss, N. Nimeh, R. TalleyG. Wampler, Neal Weinreb, J. Weisberg, R. Wheeler, P. Wiernik

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Hormonal therapy is very effective in the treatment of patients with metastatic breast cancer. Response to various therapies leads to improved quality of life and prolonged survival. This clinical trial compared two commonly utilized additive hormonal agents, tamoxifen citrate and megestrol acetate (Megace^®). Preliminary data indicate equal efficacy and equal toxicity of these two hormones and suggests that both are suitable for first-line hormonal treatment of stage IV breast cancer.

Original language	English (US)
Pages (from-to)	61-64
Number of pages	4
Journal	Seminars in oncology
Volume	12
Issue number	4 SUPPL. 6
State	Published - Dec 1985
Externally published	Yes

ASJC Scopus subject areas

Hematology
Oncology

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Allegra, J. C., Bertino, J., Bonomi, P., Byrne, P., Carpenter, J., Catalano, R., Creech, R., Dana, B., Durivage, H., Einhorn, L., Ettinger, D., Greco, F. A., Greenwald, E., Henderson, I., Holmes, F., Kinzbrunner, B., Luedke, S., Muss, H., Nimeh, N., ... Wiernik, P. (1985). Metastatic breast cancer: Preliminary results with oral hormonal therapy. Seminars in oncology, 12(4 SUPPL. 6), 61-64.

Allegra, JC, Bertino, J, Bonomi, P, Byrne, P, Carpenter, J, Catalano, R, Creech, R, Dana, B, Durivage, H, Einhorn, L, Ettinger, D, Greco, FA, Greenwald, E, Henderson, I, Holmes, F, Kinzbrunner, B, Luedke, S, Muss, H, Nimeh, N, Talley, R, Wampler, G, Weinreb, N, Weisberg, J, Wheeler, R & Wiernik, P 1985, 'Metastatic breast cancer: Preliminary results with oral hormonal therapy', Seminars in oncology, vol. 12, no. 4 SUPPL. 6, pp. 61-64.

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abstract = "Hormonal therapy is very effective in the treatment of patients with metastatic breast cancer. Response to various therapies leads to improved quality of life and prolonged survival. This clinical trial compared two commonly utilized additive hormonal agents, tamoxifen citrate and megestrol acetate (Megace{\textregistered}). Preliminary data indicate equal efficacy and equal toxicity of these two hormones and suggests that both are suitable for first-line hormonal treatment of stage IV breast cancer.",

author = "Allegra, {Joseph C.} and J. Bertino and P. Bonomi and P. Byrne and John Carpenter and R. Catalano and R. Creech and B. Dana and H. Durivage and L. Einhorn and D. Ettinger and Greco, {F. A.} and E. Greenwald and I. Henderson and F. Holmes and Barry Kinzbrunner and S. Luedke and H. Muss and N. Nimeh and R. Talley and G. Wampler and Neal Weinreb and J. Weisberg and R. Wheeler and P. Wiernik",

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T1 - Metastatic breast cancer

T2 - Preliminary results with oral hormonal therapy

AU - Allegra, Joseph C.

AU - Bertino, J.

AU - Bonomi, P.

AU - Byrne, P.

AU - Carpenter, John

AU - Catalano, R.

AU - Creech, R.

AU - Dana, B.

AU - Durivage, H.

AU - Einhorn, L.

AU - Ettinger, D.

AU - Greco, F. A.

AU - Greenwald, E.

AU - Henderson, I.

AU - Holmes, F.

AU - Kinzbrunner, Barry

AU - Luedke, S.

AU - Muss, H.

AU - Nimeh, N.

AU - Talley, R.

AU - Wampler, G.

AU - Weinreb, Neal

AU - Weisberg, J.

AU - Wheeler, R.

AU - Wiernik, P.

PY - 1985/12

Y1 - 1985/12

N2 - Hormonal therapy is very effective in the treatment of patients with metastatic breast cancer. Response to various therapies leads to improved quality of life and prolonged survival. This clinical trial compared two commonly utilized additive hormonal agents, tamoxifen citrate and megestrol acetate (Megace®). Preliminary data indicate equal efficacy and equal toxicity of these two hormones and suggests that both are suitable for first-line hormonal treatment of stage IV breast cancer.

AB - Hormonal therapy is very effective in the treatment of patients with metastatic breast cancer. Response to various therapies leads to improved quality of life and prolonged survival. This clinical trial compared two commonly utilized additive hormonal agents, tamoxifen citrate and megestrol acetate (Megace®). Preliminary data indicate equal efficacy and equal toxicity of these two hormones and suggests that both are suitable for first-line hormonal treatment of stage IV breast cancer.

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Metastatic breast cancer: Preliminary results with oral hormonal therapy

Abstract

ASJC Scopus subject areas

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