Metastatic bone disease of the humerus.

Frank J. Frassica, Deborah Frassica

Research output: Contribution to journalArticle

Abstract

Metastatic bone disease is the most common cause of destructive bone lesions in adults, and involvement of the humerus is common. Patients with destructive lesions involving or =50% of the cortex or those with pain after irradiation can be treated with intramedullary nailing to achieve rigid fixation. Although closed intramedullary nailing is used most often, open nailing with methylmethacrylate is appropriate for destructive lesions in which rigid fixation cannot be achieved with closed nailing. Plate fixation is acceptable when adequate proximal and distal cortical bone is present for screw purchase, although proximal humeral lesions usually are treated with prosthetic arthroplasty. Postoperative external beam irradiation can help prevent disease progression and subsequent loss of fixation. However, when disease progression persists or rigid internal fixation is not feasible because of extensive bone destruction, wide resection and reconstruction with a custom prosthesis can be done.

Original languageEnglish (US)
Pages (from-to)282-288
Number of pages7
JournalThe Journal of the American Academy of Orthopaedic Surgeons
Volume11
Issue number4
StatePublished - Jul 2003

Fingerprint

Intramedullary Fracture Fixation
Bone Diseases
Humerus
Disease Progression
Methylmethacrylate
Bone and Bones
Arthroplasty
Prostheses and Implants
Pain
Cortical Bone

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Metastatic bone disease of the humerus. / Frassica, Frank J.; Frassica, Deborah.

In: The Journal of the American Academy of Orthopaedic Surgeons, Vol. 11, No. 4, 07.2003, p. 282-288.

Research output: Contribution to journalArticle

Frassica, FJ & Frassica, D 2003, 'Metastatic bone disease of the humerus.', The Journal of the American Academy of Orthopaedic Surgeons, vol. 11, no. 4, pp. 282-288.
Frassica, Frank J. ; Frassica, Deborah. / Metastatic bone disease of the humerus. In: The Journal of the American Academy of Orthopaedic Surgeons. 2003 ; Vol. 11, No. 4. pp. 282-288.
@article{6c14c83bc9d64d21acc66f9bcf51f862,
title = "Metastatic bone disease of the humerus.",
abstract = "Metastatic bone disease is the most common cause of destructive bone lesions in adults, and involvement of the humerus is common. Patients with destructive lesions involving or =50{\%} of the cortex or those with pain after irradiation can be treated with intramedullary nailing to achieve rigid fixation. Although closed intramedullary nailing is used most often, open nailing with methylmethacrylate is appropriate for destructive lesions in which rigid fixation cannot be achieved with closed nailing. Plate fixation is acceptable when adequate proximal and distal cortical bone is present for screw purchase, although proximal humeral lesions usually are treated with prosthetic arthroplasty. Postoperative external beam irradiation can help prevent disease progression and subsequent loss of fixation. However, when disease progression persists or rigid internal fixation is not feasible because of extensive bone destruction, wide resection and reconstruction with a custom prosthesis can be done.",
author = "Frassica, {Frank J.} and Deborah Frassica",
year = "2003",
month = "7",
language = "English (US)",
volume = "11",
pages = "282--288",
journal = "The Journal of the American Academy of Orthopaedic Surgeons",
issn = "1067-151X",
publisher = "American Association of Orthopaedic Surgeons",
number = "4",

}

TY - JOUR

T1 - Metastatic bone disease of the humerus.

AU - Frassica, Frank J.

AU - Frassica, Deborah

PY - 2003/7

Y1 - 2003/7

N2 - Metastatic bone disease is the most common cause of destructive bone lesions in adults, and involvement of the humerus is common. Patients with destructive lesions involving or =50% of the cortex or those with pain after irradiation can be treated with intramedullary nailing to achieve rigid fixation. Although closed intramedullary nailing is used most often, open nailing with methylmethacrylate is appropriate for destructive lesions in which rigid fixation cannot be achieved with closed nailing. Plate fixation is acceptable when adequate proximal and distal cortical bone is present for screw purchase, although proximal humeral lesions usually are treated with prosthetic arthroplasty. Postoperative external beam irradiation can help prevent disease progression and subsequent loss of fixation. However, when disease progression persists or rigid internal fixation is not feasible because of extensive bone destruction, wide resection and reconstruction with a custom prosthesis can be done.

AB - Metastatic bone disease is the most common cause of destructive bone lesions in adults, and involvement of the humerus is common. Patients with destructive lesions involving or =50% of the cortex or those with pain after irradiation can be treated with intramedullary nailing to achieve rigid fixation. Although closed intramedullary nailing is used most often, open nailing with methylmethacrylate is appropriate for destructive lesions in which rigid fixation cannot be achieved with closed nailing. Plate fixation is acceptable when adequate proximal and distal cortical bone is present for screw purchase, although proximal humeral lesions usually are treated with prosthetic arthroplasty. Postoperative external beam irradiation can help prevent disease progression and subsequent loss of fixation. However, when disease progression persists or rigid internal fixation is not feasible because of extensive bone destruction, wide resection and reconstruction with a custom prosthesis can be done.

UR - http://www.scopus.com/inward/record.url?scp=0642283253&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0642283253&partnerID=8YFLogxK

M3 - Article

C2 - 12889867

AN - SCOPUS:0642283253

VL - 11

SP - 282

EP - 288

JO - The Journal of the American Academy of Orthopaedic Surgeons

JF - The Journal of the American Academy of Orthopaedic Surgeons

SN - 1067-151X

IS - 4

ER -