Metastasis-Promoting Immunity: When T Cells Turn to the Dark Side

Research output: Contribution to journalShort survey

Abstract

While the role of endogenous T cells in antitumor immunity is being debated, little is known about whether and how T cells promote tumorigenesis. In this issue of Cancer Cell, DeNardo and colleagues demonstrate that IL-4-producing T cells enhance metastasis by programming macrophages to produce factors that enhance tumor invasion.

Original languageEnglish (US)
Pages (from-to)81-82
Number of pages2
JournalCancer cell
Volume16
Issue number2
DOIs
StatePublished - Aug 4 2009

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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