Abstract
We present a case of a 34-year-old female who had a rapidly enlarging right breast mass. Biopsy results were consistent with a neuroblastic neoplasm of the breast. Neoadjuvant chemotherapy for a neuroblastoma was performed followed by a modified radical mastectomy was performed. Final pathology revealed small foci of poorly differentiated carcinoma randomly distributed within extensive areas of neuroglial differentiation. Such a lesion has not been described in the current literature to our knowledge, and we propose that this neoplasm is a metaplastic carcinoma with a novel heterogeneous differentiation. Subsequent therapy consisted of standard adjuvant breast cancer chemotherapy and radiation therapy.
Original language | English (US) |
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Pages (from-to) | 545-549 |
Number of pages | 5 |
Journal | Breast |
Volume | 15 |
Issue number | 4 |
DOIs | |
State | Published - Aug 2006 |
Externally published | Yes |
Keywords
- Metaplastic carcinoma
- Neoadjuvant chemotherapy
- Neuroglial differentiation
ASJC Scopus subject areas
- Surgery
- Oncology
- Cancer Research