Metaplastic carcinoma of the breast with neuroglial differentiation

Mehra Golshan, Adam Kuten, Jacquleine William, Andrea Richardson, Amir Modarressi, Ursula Matulonis

Research output: Contribution to journalArticle

Abstract

We present a case of a 34-year-old female who had a rapidly enlarging right breast mass. Biopsy results were consistent with a neuroblastic neoplasm of the breast. Neoadjuvant chemotherapy for a neuroblastoma was performed followed by a modified radical mastectomy was performed. Final pathology revealed small foci of poorly differentiated carcinoma randomly distributed within extensive areas of neuroglial differentiation. Such a lesion has not been described in the current literature to our knowledge, and we propose that this neoplasm is a metaplastic carcinoma with a novel heterogeneous differentiation. Subsequent therapy consisted of standard adjuvant breast cancer chemotherapy and radiation therapy.

Original languageEnglish (US)
Pages (from-to)545-549
Number of pages5
JournalBreast
Volume15
Issue number4
DOIs
StatePublished - Aug 2006
Externally publishedYes

Keywords

  • Metaplastic carcinoma
  • Neoadjuvant chemotherapy
  • Neuroglial differentiation

ASJC Scopus subject areas

  • Surgery

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  • Cite this

    Golshan, M., Kuten, A., William, J., Richardson, A., Modarressi, A., & Matulonis, U. (2006). Metaplastic carcinoma of the breast with neuroglial differentiation. Breast, 15(4), 545-549. https://doi.org/10.1016/j.breast.2005.09.003