Metabolomics of urinary tract infection: A new uroscope in town

Ashish Gupta, Navneeta Bansal, Brian Houston

Research output: Contribution to journalArticle

Abstract

Urinary tract infection (UTI) is a potentially life-threatening infectious disease. For rapid directed therapy of UTIs, it is essential to determine the causative microorganism. To date, there is no single test that has been proven to reliably, rapidly and accurately identify the etiologic organism in UTI. The molecular methods for diagnosing the cause of UTI and prognostic development of clinically important metabolomic evaluations and their limitations for use in the diagnosis and monitoring of infections are discussed in this review article. The application of the emerging investigative device NMR spectroscopy as a surrogate method for the diagnosis of UTI is also addressed.

Original languageEnglish (US)
Pages (from-to)361-369
Number of pages9
JournalExpert Review of Molecular Diagnostics
Volume12
Issue number4
DOIs
Publication statusPublished - May 2012

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Keywords

  • diagnostic
  • metabolomics
  • NMR
  • urinary tract infection

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Pathology and Forensic Medicine

Cite this

Metabolomics of urinary tract infection : A new uroscope in town. / Gupta, Ashish; Bansal, Navneeta; Houston, Brian.

In: Expert Review of Molecular Diagnostics, Vol. 12, No. 4, 05.2012, p. 361-369.

Research output: Contribution to journalArticle