Metabolomics of urinary tract infection: A new uroscope in town

Ashish Gupta, Navneeta Bansal, Brian Houston

Research output: Contribution to journalReview articlepeer-review

Abstract

Urinary tract infection (UTI) is a potentially life-threatening infectious disease. For rapid directed therapy of UTIs, it is essential to determine the causative microorganism. To date, there is no single test that has been proven to reliably, rapidly and accurately identify the etiologic organism in UTI. The molecular methods for diagnosing the cause of UTI and prognostic development of clinically important metabolomic evaluations and their limitations for use in the diagnosis and monitoring of infections are discussed in this review article. The application of the emerging investigative device NMR spectroscopy as a surrogate method for the diagnosis of UTI is also addressed.

Original languageEnglish (US)
Pages (from-to)361-369
Number of pages9
JournalExpert Review of Molecular Diagnostics
Volume12
Issue number4
DOIs
StatePublished - May 1 2012

Keywords

  • NMR
  • diagnostic
  • metabolomics
  • urinary tract infection

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Medicine
  • Molecular Biology
  • Genetics

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