Metabolic syndrome risk profiles among African American adolescents National Health and Nutrition Examination Survey, 2003-2010

Stephanie L. Fitzpatrick, Betty S. Lai, Frederick L. Brancati, Sherita Hill Golden, Felicia Hill-Briggs

Research output: Contribution to journalArticle

Abstract

OBJECTIVE-Although African American adolescents have the highest prevalence of obesity, they have the lowest prevalence of metabolic syndrome across all definitions used in previous research. To address this paradox, we sought to develop a model of the metabolic syndrome specific to African American adolescents. RESEARCH DESIGN AND METHODS-Data from the National Health and Nutrition Examination Survey (2003-2010) of 822 nonpregnant, nondiabetic, African American adolescents (45% girls; aged 12 to 17 years) who underwent physical examinations and fasted at least 8 h were analyzed. We conducted a confirmatory factor analysis to model metabolic syndrome and then used latent profile analysis to identify metabolic syndrome risk groups among African American adolescents. We compared the risk groups on probability of prediabetes. RESULTS-The best-fitting metabolic syndrome model consisted of waist circumference, fasting insulin, HDL, and systolic blood pressure. We identified three metabolic syndrome risk groups: low, moderate, and high risk (19% boys; 16% girls). Thirty-five percent of both boys and girls in the high-risk groups had prediabetes, a significantly higher prevalence compared with boys and girls in the low-risk groups. Among adolescents with BMI higher than the 85th per-centile, 48 and 36% of boys and girls, respectively, were in the high-risk group. CONCLUSIONS-Our findings provide a plausible model of the metabolic syndrome specific to African American adolescents. Based on this model, approximately 19 and 16% of African American boys and girls, respectively, are at high risk for having the metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)436-442
Number of pages7
JournalDiabetes Care
Volume36
Issue number2
DOIs
StatePublished - Feb 2013

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Nutrition Surveys
African Americans
Prediabetic State
Blood Pressure
Adolescent Health
Waist Circumference
Statistical Factor Analysis
Physical Examination
Fasting
Research Design
Obesity
Insulin
Research

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

Cite this

Metabolic syndrome risk profiles among African American adolescents National Health and Nutrition Examination Survey, 2003-2010. / Fitzpatrick, Stephanie L.; Lai, Betty S.; Brancati, Frederick L.; Golden, Sherita Hill; Hill-Briggs, Felicia.

In: Diabetes Care, Vol. 36, No. 2, 02.2013, p. 436-442.

Research output: Contribution to journalArticle

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abstract = "OBJECTIVE-Although African American adolescents have the highest prevalence of obesity, they have the lowest prevalence of metabolic syndrome across all definitions used in previous research. To address this paradox, we sought to develop a model of the metabolic syndrome specific to African American adolescents. RESEARCH DESIGN AND METHODS-Data from the National Health and Nutrition Examination Survey (2003-2010) of 822 nonpregnant, nondiabetic, African American adolescents (45{\%} girls; aged 12 to 17 years) who underwent physical examinations and fasted at least 8 h were analyzed. We conducted a confirmatory factor analysis to model metabolic syndrome and then used latent profile analysis to identify metabolic syndrome risk groups among African American adolescents. We compared the risk groups on probability of prediabetes. RESULTS-The best-fitting metabolic syndrome model consisted of waist circumference, fasting insulin, HDL, and systolic blood pressure. We identified three metabolic syndrome risk groups: low, moderate, and high risk (19{\%} boys; 16{\%} girls). Thirty-five percent of both boys and girls in the high-risk groups had prediabetes, a significantly higher prevalence compared with boys and girls in the low-risk groups. Among adolescents with BMI higher than the 85th per-centile, 48 and 36{\%} of boys and girls, respectively, were in the high-risk group. CONCLUSIONS-Our findings provide a plausible model of the metabolic syndrome specific to African American adolescents. Based on this model, approximately 19 and 16{\%} of African American boys and girls, respectively, are at high risk for having the metabolic syndrome.",
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