The metabolic myopathies are a heterogeneous group of diseases characterized by impaired skeletal muscle energy production. Primary metabolic myopathies are associated with genetically determined defects in glycogen and lipid metabolism and in mitochondrial oxidative phosphorylation. These include the muscle glycogenoses and the lipid and mitochondrial myopathies. Other metabolic myopathies arise from endocrine or electrolyte abnormalities and therapy with specific drugs. A classification of the primary metabolic myopathies is presented in Table 19-1.
|Original language||English (US)|
|Title of host publication||Primer on the Rheumatic Diseases|
|Subtitle of host publication||Thirteenth Edition|
|Publisher||Springer New York|
|Number of pages||8|
|State||Published - Dec 1 2008|
ASJC Scopus subject areas