Translated title of the contribution: Meta-analysis: Its role in clinical decision-making in cardiology

E. Guallar, J. R. Banegas, J. M. Martin-Moreno, A. Del Rio

Research output: Contribution to journalShort survey


Clinical decision-making in cardiology requires accurate estimates of the efficacy of diagnostic and therapeutic procedures. Defined as the quantitative integration of results from different studies on the same scientific question, meta-analyses are well-suited to summarize the evidence on the efficacy of clinical interventions. Meta-analyses aim at obtaining combined estimates of effect using all relevant information in a systematic fashion, complementing narrative reviews and expert committee reports. In this paper, the advantages and limitations of meta-analyses and their usefulness in clinical decision making in cardiology are illustrated using three recent examples in the literature - i.e. use of β-blockers in secondary prevention of ischemic heart disease, intravenous streptokinase in acute myocardial infarction and fish intake in primary prevention of cardiovascular mortality. The steps to follow when conducting a meta-analysis are also discussed. Finally, a list of the most important meta-analyses in cardiology published to date is included for easy reference.

Translated title of the contributionMeta-analysis: Its role in clinical decision-making in cardiology
Original languageSpanish
Pages (from-to)509-517
Number of pages9
JournalRevista Espanola de Cardiologia
Issue number8
StatePublished - Jan 1 1994
Externally publishedYes


  • clinical decision-making
  • efficacy of cardiological procedures
  • health technology assessment
  • meta-analysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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  • Cite this

    Guallar, E., Banegas, J. R., Martin-Moreno, J. M., & Del Rio, A. (1994). METAANALISIS: SU IMPORTANCIA EN LA TOMA DE DECISIONES CLINICAS EN CARDIOLOGIA. Revista Espanola de Cardiologia, 47(8), 509-517.