Mesial temporal lobe measurements on magnetic resonance imaging scans

Nancy A. Honeycutt, Paige D. Smith, Elizabeth Aylward, Qiang Li, Michael Chan, Patrick E. Barta, Godfrey D. Pearlson

Research output: Contribution to journalArticle


Changes in the mesial temporal lobe, particularly in the hippocampus, amygdala, and entorhinal cortex, are reported to occur in several neuropsychiatric conditions. Neuroimaging provides a non-invasive means of studying these changes. We present a method for reliably measuring the hippocampus, amygdala, and entorhinal cortex on MRI. The advantages of our method include high reliability, the use of orthogonal views in delineating boundaries and circumscription of measurement such that no tissue of any one anatomic structure is included in the measurement of another structure.

Original languageEnglish (US)
Pages (from-to)85-94
Number of pages10
JournalPsychiatry Research - Neuroimaging
Issue number2
StatePublished - Aug 26 1998



  • Amygdala
  • Entorhinal cortex
  • Hippocampus

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

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