Membranous glomerulonephropathy with crescents in systemic lupus erythematosus

Winston W. Williams, Dipak J. Shah, Anthony G. Morgan, George A O Alleyne

Research output: Contribution to journalArticlepeer-review

Abstract

Over a 2-ycar period percutaneous renal biopsies were carried out on 23 patients with systemic lupus nephritis. When classified by immunofluorescence, and light and electron microscopy, 4 patients had mesangial disease. 1 had focal and segmental proliferation, 5 had diffuse proliferation and 5 had membranous changes. 3 biopsies were unclassifiable with end-stage changes and 5 showed an unusual combination of pure membranous changes in association with significant crescent formation. The outcome of the latter group of patients was uniformly poor. We think that this group represents a distinct histological entity with a poor prognosis.

Original languageEnglish (US)
Pages (from-to)158-162
Number of pages5
JournalAmerican Journal of Nephrology
Volume5
Issue number3
DOIs
StatePublished - 1985
Externally publishedYes

Keywords

  • Crescents
  • Lupus nephritis
  • Membranous glomerulonephropathy

ASJC Scopus subject areas

  • Nephrology

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