Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery

Kristen Nelson-McMillan; William J. Ravekes; William R. Thompson; Kristen M. Brown; Larry Wolff; Rajeev S. Wadia; Le Ann M. McNamara; Donald H. Shaffner; Ivor D. Berkowitz; Marshall L. Jacobs; Luca A. Vricella

doi:10.1177/2150135116668832

Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery

Kristen Nelson-McMillan, William J. Ravekes, William R. Thompson, Kristen M. Brown, Larry Wolff, Rajeev S. Wadia, Le Ann M. McNamara, Donald H. Shaffner, Ivor D. Berkowitz, Marshall L. Jacobs, Luca A. Vricella

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support. Oxygenator placement enabled transition to conventional ventilation and the discontinuation of vasopressor support. This case demonstrates the feasibility and safety of the use of this lung support system in patients requiring ventricular assist device (VAD) support.

Original language	English (US)
Pages (from-to)	105-109
Number of pages	5
Journal	World Journal for Pediatric and Congenital Heart Surgery
Volume	9
Issue number	1
DOIs	https://doi.org/10.1177/2150135116668832
State	Published - Jan 1 2018

Keywords

circulatory assist devices
heart failure
pediatric
pulmonary vascular resistance/hypertension

ASJC Scopus subject areas

Surgery
Pediatrics, Perinatology, and Child Health
Cardiology and Cardiovascular Medicine

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10.1177/2150135116668832

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Nelson-McMillan, K., Ravekes, W. J., Thompson, W. R., Brown, K. M., Wolff, L., Wadia, R. S., McNamara, L. A. M., Shaffner, D. H., Berkowitz, I. D., Jacobs, M. L., & Vricella, L. A. (2018). Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery. World Journal for Pediatric and Congenital Heart Surgery, 9(1), 105-109. https://doi.org/10.1177/2150135116668832

Nelson-McMillan, K, Ravekes, WJ , Thompson, WR , Brown, KM, Wolff, L, Wadia, RS, McNamara, LAM, Shaffner, DH , Berkowitz, ID , Jacobs, ML & Vricella, LA 2018, 'Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery', World Journal for Pediatric and Congenital Heart Surgery, vol. 9, no. 1, pp. 105-109. https://doi.org/10.1177/2150135116668832

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abstract = "We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support. Oxygenator placement enabled transition to conventional ventilation and the discontinuation of vasopressor support. This case demonstrates the feasibility and safety of the use of this lung support system in patients requiring ventricular assist device (VAD) support.",

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AU - Wolff, Larry

AU - Wadia, Rajeev S.

AU - McNamara, Le Ann M.

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Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery

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