Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery

Research output: Contribution to journalArticle

Abstract

We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support. Oxygenator placement enabled transition to conventional ventilation and the discontinuation of vasopressor support. This case demonstrates the feasibility and safety of the use of this lung support system in patients requiring ventricular assist device (VAD) support.

Original languageEnglish (US)
Pages (from-to)105-109
Number of pages5
JournalWorld journal for pediatric & congenital heart surgery
Volume9
Issue number1
DOIs
StatePublished - Jan 1 2018

Fingerprint

Membrane Oxygenators
Heart-Assist Devices
High-Frequency Ventilation
Berlin
Equipment and Supplies
Lung
Respiratory Acidosis
Oxygenators
Adult Respiratory Distress Syndrome
Acidosis
Cytomegalovirus
Ventilation
Pneumonia
Safety
Pressure

Keywords

  • circulatory assist devices
  • heart failure
  • pediatric
  • pulmonary vascular resistance/hypertension

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Membrane Oxygenator Use With Biventricular Assist Device: Facilitation of Support and Lung Recovery",
abstract = "We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support. Oxygenator placement enabled transition to conventional ventilation and the discontinuation of vasopressor support. This case demonstrates the feasibility and safety of the use of this lung support system in patients requiring ventricular assist device (VAD) support.",
keywords = "circulatory assist devices, heart failure, pediatric, pulmonary vascular resistance/hypertension",
author = "Kristen Nelson-McMillan and William Ravekes and Reid Thompson and Kristen Brown and Larry Wolff and Rajeev Wadia and McNamara, {Le Ann M.} and Shaffner, {Donald Harry} and Berkowitz, {Ivor David} and Jacobs, {Marshall L} and Luca Vricella",
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AU - Nelson-McMillan, Kristen

AU - Ravekes, William

AU - Thompson, Reid

AU - Brown, Kristen

AU - Wolff, Larry

AU - Wadia, Rajeev

AU - McNamara, Le Ann M.

AU - Shaffner, Donald Harry

AU - Berkowitz, Ivor David

AU - Jacobs, Marshall L

AU - Vricella, Luca

PY - 2018/1/1

Y1 - 2018/1/1

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AB - We present the use of a low-resistance membrane oxygenator (Quadrox D, Maquet) in series with a pulsatile right ventricular assist device (Berlin Heart EXCOR, Berlin Heart) in a patient with biventricular support who required high-frequency oscillatory ventilation (HFOV), due to refractory acute respiratory distress syndrome associated with Cytomegalovirus pneumonia. The high mean airway pressure associated with the use of HFOV resulted in a significant negative impact on left ventricular assist device (LVAD) filling that led to a combined respiratory and metabolic acidosis and the need for vasopressor support. Oxygenator placement enabled transition to conventional ventilation and the discontinuation of vasopressor support. This case demonstrates the feasibility and safety of the use of this lung support system in patients requiring ventricular assist device (VAD) support.

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KW - heart failure

KW - pediatric

KW - pulmonary vascular resistance/hypertension

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