TY - JOUR
T1 - Meeting report immune-mediated drug hypersensitivity reactions (IDHR) workshop
AU - Kawabata, Thomas T.
AU - Haggerty, Helen G.
AU - Lavin, Amy L.
AU - Adkinson, N. Franklin
AU - Holsapple, Mike
N1 - Funding Information:
Richard Okita (National Institute of General Medical Sciences, NIH) reviewed the history of IDHR grants funded by the NIH using the CRISP (Computer Retrieval of Information on Scientific Projects) database. He indicated that only three RO1 research grants in the area of IDHR were funded by the NIH in 2003. Similar numbers of IDHR grants were funded in 2001 and 2002. These grants focused on drug metabolism/activation and it relationship to IDHR, pharmacogenetics of IDHR, IDHR in AIDS patients, pediatric drug allergy and incidence of IDHR associated with the use of anesthetics. Dr. Okita indicated that the lack of significant funding in the area of IDHR research is due to a number of reasons, including lack of demand from public stakeholders, lack of funding applications directed at IDHR research, and the lack of specific training in IDHR scientific approaches.
PY - 2005
Y1 - 2005
N2 - Immune-mediated drug hypersensitivity reactions (IDHR) are relatively rare reactions to drugs that can be observed in a limited population of patients, yet these reactions can have significant impacts on public health, clinical practice, and drug development. Despite the potentially significant impact of IDHR, research into the causes and mechanisms of action of these reactions has been limited. In order to identify and enhance potential research opportunities in IDHR, the Health and Environmental Sciences Institute (HESI) hosted a two-day workshop involving stakeholders from government, academia, and industry. Discussions focused on ways to increase IDHR research opportunities within both presently existing collaborative structures and new networks. Based on these discussions, workshop participants concluded that a volunteer organization of interested stakeholders could be established to provide for ongoing advocacy and coordination of efforts related to IDHR research. The primary objectives of such an organization would be to increase public awareness of the impact of IDHR, encourage multidisciplinary IDHR research and training, encourage the development and funding of IDHR research network and seed grants, and to establish a framework for the further exchange and dissemination of IDHR information.
AB - Immune-mediated drug hypersensitivity reactions (IDHR) are relatively rare reactions to drugs that can be observed in a limited population of patients, yet these reactions can have significant impacts on public health, clinical practice, and drug development. Despite the potentially significant impact of IDHR, research into the causes and mechanisms of action of these reactions has been limited. In order to identify and enhance potential research opportunities in IDHR, the Health and Environmental Sciences Institute (HESI) hosted a two-day workshop involving stakeholders from government, academia, and industry. Discussions focused on ways to increase IDHR research opportunities within both presently existing collaborative structures and new networks. Based on these discussions, workshop participants concluded that a volunteer organization of interested stakeholders could be established to provide for ongoing advocacy and coordination of efforts related to IDHR research. The primary objectives of such an organization would be to increase public awareness of the impact of IDHR, encourage multidisciplinary IDHR research and training, encourage the development and funding of IDHR research network and seed grants, and to establish a framework for the further exchange and dissemination of IDHR information.
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U2 - 10.1080/15476910490898135
DO - 10.1080/15476910490898135
M3 - Review article
C2 - 18958653
AN - SCOPUS:67649307801
SN - 1547-691X
VL - 1
SP - 201
EP - 205
JO - Journal of Immunotoxicology
JF - Journal of Immunotoxicology
IS - 3-4
ER -