Medical versus medical and surgical treatment for brucella endocarditis

Maryam Keshtkar-Jahromi, Seyed Mostafa Razavi, Sharareh Gholamin, Marzieh Keshtkar-Jahromi, Mian Hossain, Mohammad M. Sajadi

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


This review was undertaken to determine the role of surgery in the treatment of brucella endocarditis. All English and French articles reporting brucella endocarditis (1966 to 2011) in PubMed, Google, and Scopus were reviewed. In all, 308 cases were identified, and linear and logistic regression was performed. Surgery improved outcomes by decreasing mortality from 32.7% in the medical treatment only group to 6.7% in the combined surgical and medical treatment group (p < 0.001). This association was still significant while controlling for other contributing factors. In the absence of a controlled trial, we recommend the utmost vigilance and consideration of surgical management in treating such patients.

Original languageEnglish (US)
Pages (from-to)2141-2146
Number of pages6
JournalAnnals of Thoracic Surgery
Issue number6
StatePublished - Dec 2012
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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