Medical evaluation and management of urolithiasis

Michelle jo Semins, Brian R. Matlaga

Research output: Contribution to journalReview article


Nephrolithiasis is a highly prevalent condition with a high recurrence rate that has a large impact on the quality of life of those affected. It also poses a great financial burden on society. There have been great advancements in the surgical treatment of stone disease over the past several decades. The evolution of surgical technique appears to have overshadowed the importance of prevention of stone disease despite evidence showing medical therapies significantly decreasing stone recurrence rates. Herein we review the metabolic evaluation of stone formers with the use of specific blood and urine tests. We complete our discussion with a review of the medical management of stone formers providing both general recommendations as well as reviewing focused therapies for specific metabolic abnormalities and medical conditions.

Original languageEnglish (US)
Pages (from-to)3-9
Number of pages7
JournalTherapeutic Advances in Urology
Issue number1
StatePublished - Feb 2010



  • calculi
  • kidney
  • metabolic evaluation
  • nephrolithiasis
  • prevention

ASJC Scopus subject areas

  • Urology

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