Mediastinal mass due to Aspergillus fumigatus after lung transplantation: A case report

Oksana Anatolia Shlobin, Lesia K. Dropulic, Jonathan B. Orens, John F. Mcdyer, John V. Conte, Stephen Y. Yang, Reda Girgis

Research output: Contribution to journalArticle

Abstract

We report a rare case of mediastinal mass caused by Aspergillus fumigatus in a lung transplant recipient. The patient presented 9 months after bilateral lung transplantation for cystic fibrosis with intermittent fevers and new onset atrial fibrillation/flutter caused by a 7-cm mediastinal mass invading the left atrium. The mass was resected, and a prolonged course of voriconazole and caspofungin was given, which resulted in a complete clinical response. Despite long-term suppressive therapy with voriconazole, a relapse occurred 16 months after the initial diagnosis. This case highlights the challenges in the prevention and treatment of invasive aspergillosis in lung transplant recipients.

Original languageEnglish (US)
Pages (from-to)1991-1994
Number of pages4
JournalJournal of Heart and Lung Transplantation
Volume24
Issue number11
DOIs
StatePublished - Nov 1 2005

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

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