Mediastinal mass due to Aspergillus fumigatus after lung transplantation

A case report

Oksana Anatolia Shlobin, Lesia K. Dropulic, Jonathan B Orens, John F. Mcdyer, John V. Conte, Stephen C Yang, Reda Girgis

Research output: Contribution to journalArticle

Abstract

We report a rare case of mediastinal mass caused by Aspergillus fumigatus in a lung transplant recipient. The patient presented 9 months after bilateral lung transplantation for cystic fibrosis with intermittent fevers and new onset atrial fibrillation/flutter caused by a 7-cm mediastinal mass invading the left atrium. The mass was resected, and a prolonged course of voriconazole and caspofungin was given, which resulted in a complete clinical response. Despite long-term suppressive therapy with voriconazole, a relapse occurred 16 months after the initial diagnosis. This case highlights the challenges in the prevention and treatment of invasive aspergillosis in lung transplant recipients.

Original languageEnglish (US)
Pages (from-to)1991-1994
Number of pages4
JournalJournal of Heart and Lung Transplantation
Volume24
Issue number11
DOIs
StatePublished - Nov 2005

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Aspergillus fumigatus
Lung Transplantation
caspofungin
Pulmonary Aspergillosis
Atrial Flutter
Heart Atria
Cystic Fibrosis
Atrial Fibrillation
Fever
Recurrence
Lung
Therapeutics
Voriconazole
Transplant Recipients

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Transplantation

Cite this

Mediastinal mass due to Aspergillus fumigatus after lung transplantation : A case report. / Shlobin, Oksana Anatolia; Dropulic, Lesia K.; Orens, Jonathan B; Mcdyer, John F.; Conte, John V.; Yang, Stephen C; Girgis, Reda.

In: Journal of Heart and Lung Transplantation, Vol. 24, No. 11, 11.2005, p. 1991-1994.

Research output: Contribution to journalArticle

Shlobin, Oksana Anatolia ; Dropulic, Lesia K. ; Orens, Jonathan B ; Mcdyer, John F. ; Conte, John V. ; Yang, Stephen C ; Girgis, Reda. / Mediastinal mass due to Aspergillus fumigatus after lung transplantation : A case report. In: Journal of Heart and Lung Transplantation. 2005 ; Vol. 24, No. 11. pp. 1991-1994.
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