Mediastinal fibrosis of the pulmonary artery secondary to tuberculosis

Oluseyi Ojeifo; Nisha A. Gilotra; Clinton D. Kemp; Andrew Leventhal; Jon Resar; Kenton J. Zehr; Steve Jones

doi:10.1016/j.athoracsur.2015.03.113

Mediastinal fibrosis of the pulmonary artery secondary to tuberculosis

Oluseyi Ojeifo, Nisha A. Gilotra, Clinton D. Kemp, Andrew Leventhal, Jon Resar, Kenton J. Zehr, Steve Jones

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Mediastinal fibrosis is an uncommon disease involving the esophagus, respiratory tract, and great vessels. We report a man who presented with dyspnea on exertion. Computed tomography of the chest demonstrated granulomatous disease with dense calcifications leading to severe stenosis of the main pulmonary artery (PA) and narrowing of the superior vena cava. The results of tuberculosis (TB) interferon-γ release assay and TB-polymerase chain reaction were positive for Mycobacterium tuberculosis. The patient received 2 weeks of treatment for latent TB before undergoing resection of fibrotic tissue and replacement of the main and branch PAs using a homograft.

Original language	English (US)
Pages (from-to)	e49-e50
Journal	Annals of Thoracic Surgery
Volume	100
Issue number	3
DOIs	https://doi.org/10.1016/j.athoracsur.2015.03.113
State	Published - Sep 1 2015

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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title = "Mediastinal fibrosis of the pulmonary artery secondary to tuberculosis",

abstract = "Mediastinal fibrosis is an uncommon disease involving the esophagus, respiratory tract, and great vessels. We report a man who presented with dyspnea on exertion. Computed tomography of the chest demonstrated granulomatous disease with dense calcifications leading to severe stenosis of the main pulmonary artery (PA) and narrowing of the superior vena cava. The results of tuberculosis (TB) interferon-γ release assay and TB-polymerase chain reaction were positive for Mycobacterium tuberculosis. The patient received 2 weeks of treatment for latent TB before undergoing resection of fibrotic tissue and replacement of the main and branch PAs using a homograft.",

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AU - Ojeifo, Oluseyi

AU - Gilotra, Nisha A.

AU - Kemp, Clinton D.

AU - Leventhal, Andrew

AU - Resar, Jon

AU - Zehr, Kenton J.

AU - Jones, Steve

PY - 2015/9/1

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N2 - Mediastinal fibrosis is an uncommon disease involving the esophagus, respiratory tract, and great vessels. We report a man who presented with dyspnea on exertion. Computed tomography of the chest demonstrated granulomatous disease with dense calcifications leading to severe stenosis of the main pulmonary artery (PA) and narrowing of the superior vena cava. The results of tuberculosis (TB) interferon-γ release assay and TB-polymerase chain reaction were positive for Mycobacterium tuberculosis. The patient received 2 weeks of treatment for latent TB before undergoing resection of fibrotic tissue and replacement of the main and branch PAs using a homograft.

AB - Mediastinal fibrosis is an uncommon disease involving the esophagus, respiratory tract, and great vessels. We report a man who presented with dyspnea on exertion. Computed tomography of the chest demonstrated granulomatous disease with dense calcifications leading to severe stenosis of the main pulmonary artery (PA) and narrowing of the superior vena cava. The results of tuberculosis (TB) interferon-γ release assay and TB-polymerase chain reaction were positive for Mycobacterium tuberculosis. The patient received 2 weeks of treatment for latent TB before undergoing resection of fibrotic tissue and replacement of the main and branch PAs using a homograft.

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Mediastinal fibrosis of the pulmonary artery secondary to tuberculosis

Abstract

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