Mechano-electric interactions and their role in electrical function of the heart

J. Jeremy Rice, Peter Kohl

Research output: Chapter in Book/Report/Conference proceedingChapter


The heart is an electrically controlled and chemically powered mechanical pump. There are complex interactions between cardiac structure and function, including electrophysiology, metabolism, and mechanics. These are based on a multitude of interdigitating regulatory loops with different inherent time-scales. This chapter will focus on the acute cross-talk between electrical and mechanical activity of the heart, and in particular its relevance for normal and abnormal heart rhythms.

Original languageEnglish (US)
Title of host publicationBasic Foundations and Primary Electrical Diseases
PublisherSpringer-Verlag London Ltd
Number of pages19
ISBN (Electronic)9781447148814
ISBN (Print)1447148800, 9781447148807
StatePublished - Mar 1 2013
Externally publishedYes


  • Calcium handling
  • Cardiomyocyte
  • Excitation-contraction coupling
  • Heart
  • Mechano-electric coupling/mechano-electric feedback
  • Stretch
  • Stretch-activated channel

ASJC Scopus subject areas

  • Medicine(all)


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