Mechanisms of neurotoxicity as studied in tissue culture systems

Alan M. Goldberg

doi:10.1016/0300-483X(80)90095-5

Mechanisms of neurotoxicity as studied in tissue culture systems

Alan M. Goldberg

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

This presentation focused on describing the unique aspects of nervous tissue which make it susceptible to toxicological insult. It reviewed the published literature of compounds that have been studied in tissue culture of nerve tissue and compared the data in vivo toxicity studies with that obtained from the tissue culture system. Further, neuronal activity as a determinant of neurotoxicity was discussed as a basic mechanism to understand toxicological outcomes.

Original language	English (US)
Pages (from-to)	201-208
Number of pages	8
Journal	Toxicology
Volume	17
Issue number	2
DOIs	https://doi.org/10.1016/0300-483X(80)90095-5
State	Published - 1980

ASJC Scopus subject areas

Toxicology

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10.1016/0300-483X(80)90095-5

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abstract = "This presentation focused on describing the unique aspects of nervous tissue which make it susceptible to toxicological insult. It reviewed the published literature of compounds that have been studied in tissue culture of nerve tissue and compared the data in vivo toxicity studies with that obtained from the tissue culture system. Further, neuronal activity as a determinant of neurotoxicity was discussed as a basic mechanism to understand toxicological outcomes.",

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Mechanisms of neurotoxicity as studied in tissue culture systems

Abstract

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