Mechanisms of neurotoxicity as studied in tissue culture systems

Research output: Contribution to journalArticlepeer-review


This presentation focused on describing the unique aspects of nervous tissue which make it susceptible to toxicological insult. It reviewed the published literature of compounds that have been studied in tissue culture of nerve tissue and compared the data in vivo toxicity studies with that obtained from the tissue culture system. Further, neuronal activity as a determinant of neurotoxicity was discussed as a basic mechanism to understand toxicological outcomes.

Original languageEnglish (US)
Pages (from-to)201-208
Number of pages8
Issue number2
StatePublished - 1980

ASJC Scopus subject areas

  • Toxicology


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