Mechanisms of Immune Evasion by Tumors

Research output: Contribution to journalReview articlepeer-review

453 Scopus citations


In the past decade, basic studies in animal models have begun to elucidate the physiological barriers which impede a successful antitumor immune response. These barriers operate at a number of levels, and involve the tumor, the tumor microenvironment and various components of the innate and adaptive immune systems. In this review, we discuss the multiple mechanisms by which tumors evade an immune response, with an emphasis on clinically relevant strategies to overcome these inhibitory checkpoints.

Original languageEnglish (US)
Pages (from-to)51-81
Number of pages31
JournalAdvances in Immunology
StatePublished - 2006

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


Dive into the research topics of 'Mechanisms of Immune Evasion by Tumors'. Together they form a unique fingerprint.

Cite this