Mechanisms of Cerebral Injury from Cardiac Surgery

Charles W. Hogue, Rebecca F. Gottesman, Joshua Stearns

Research output: Contribution to journalReview article


Cerebral injury is a frequent complication of cardiac surgery, and it has been associated with high mortality, morbidity, hospital costs; an increased likelihood of admission to a secondary care facility after hospital discharge; and impaired quality of life. This article examines postulated mechanisms for cerebral injury from cardiac surgery. Most emphasis has been placed in the past on the intraoperative interval as being the period of highest cerebral vulnerability. Many clinical cerebral events, however, occur in the postoperative period.

Original languageEnglish (US)
Pages (from-to)83-98
Number of pages16
JournalCritical Care Clinics
Issue number1
StatePublished - Jan 2008


ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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