TY - JOUR
T1 - Mechanisms of Cerebral Injury from Cardiac Surgery
AU - Hogue, Charles W.
AU - Gottesman, Rebecca F.
AU - Stearns, Joshua
PY - 2008/1
Y1 - 2008/1
N2 - Cerebral injury is a frequent complication of cardiac surgery, and it has been associated with high mortality, morbidity, hospital costs; an increased likelihood of admission to a secondary care facility after hospital discharge; and impaired quality of life. This article examines postulated mechanisms for cerebral injury from cardiac surgery. Most emphasis has been placed in the past on the intraoperative interval as being the period of highest cerebral vulnerability. Many clinical cerebral events, however, occur in the postoperative period.
AB - Cerebral injury is a frequent complication of cardiac surgery, and it has been associated with high mortality, morbidity, hospital costs; an increased likelihood of admission to a secondary care facility after hospital discharge; and impaired quality of life. This article examines postulated mechanisms for cerebral injury from cardiac surgery. Most emphasis has been placed in the past on the intraoperative interval as being the period of highest cerebral vulnerability. Many clinical cerebral events, however, occur in the postoperative period.
UR - http://www.scopus.com/inward/record.url?scp=38649114706&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=38649114706&partnerID=8YFLogxK
U2 - 10.1016/j.ccc.2007.09.004
DO - 10.1016/j.ccc.2007.09.004
M3 - Review article
C2 - 18241780
AN - SCOPUS:38649114706
SN - 0749-0704
VL - 24
SP - 83
EP - 98
JO - Critical care clinics
JF - Critical care clinics
IS - 1
ER -