We have demonstrated that treatment with either superoxide dismutase, a scavenger of superoxide radicals, or allopurinol, an inhibitor of xanthine oxidase, significantly increases the survival of island skin flaps following ischemia. We further investigated the mechanism of ischemia/reperfusion injury following a prolonged arteriovenous occlusion in island skin flaps in rats.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Jan 1 1985|
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