Mechanism and prevention of ischemia/reperfusion injury in island skin flaps

K. K. Narayan, M. J. Im, P. N. Manson

Research output: Contribution to journalArticlepeer-review

Abstract

We have demonstrated that treatment with either superoxide dismutase, a scavenger of superoxide radicals, or allopurinol, an inhibitor of xanthine oxidase, significantly increases the survival of island skin flaps following ischemia. We further investigated the mechanism of ischemia/reperfusion injury following a prolonged arteriovenous occlusion in island skin flaps in rats.

Original languageEnglish (US)
Pages (from-to)593-595
Number of pages3
JournalSurgical forum
VolumeVOL. 36
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Surgery

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