Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy

Joevin Sourdon; Sabra C. Lewsey; Michael Schär; Robert G. Weiss

doi:10.1016/j.hfc.2020.08.011

Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy

Joevin Sourdon, Sabra C. Lewsey, Michael Schär, Robert G. Weiss

School of Medicine

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.

Original language	English (US)
Pages (from-to)	149-156
Number of pages	8
Journal	Heart Failure Clinics
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/j.hfc.2020.08.011
State	Published - Jan 2021

Keywords

Cardiac magnetic resonance
Cardiomyopathies
Energetics
Heart failure
Metabolism
Spectroscopy

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.hfc.2020.08.011

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title = "Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy",

abstract = "The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.",

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AU - Sourdon, Joevin

AU - Lewsey, Sabra C.

AU - Schär, Michael

AU - Weiss, Robert G.

PY - 2021/1

Y1 - 2021/1

N2 - The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.

AB - The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.

KW - Cardiac magnetic resonance

KW - Cardiomyopathies

KW - Energetics

KW - Heart failure

KW - Metabolism

KW - Spectroscopy

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Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy

Abstract

Keywords

ASJC Scopus subject areas

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