Measures of genotoxicity in Gulf war I veterans exposed to depleted uranium

Melissa A. Mcdiarmid, Richard J. Albertini, James D. Tucker, Pamela M. Vacek, Elizabeth W. Carter, Marina V. Bakhmutsky, Marc S. Oliver, Susan M. Engelhardt, Katherine S. Squibb

Research output: Contribution to journalArticle

Abstract

Exposure to depleted uranium (DU), an alpha-emitting heavy metal, has prompted the inclusion of markers of genotoxicity in the long-term medical surveillance of a cohort of DU-exposed Gulf War veterans followed since 1994. Using urine U (uU) concentration as the measure of U body burden, the cohort has been stratified into low-u (

Original languageEnglish (US)
Pages (from-to)569-581
Number of pages13
JournalEnvironmental and Molecular Mutagenesis
Volume52
Issue number7
DOIs
StatePublished - Aug 2011
Externally publishedYes

Keywords

  • Biomarkers of genotoxicity
  • Depleted uranium
  • HPRT mutations
  • Human carcinogenicity

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Epidemiology
  • Genetics(clinical)

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  • Cite this

    Mcdiarmid, M. A., Albertini, R. J., Tucker, J. D., Vacek, P. M., Carter, E. W., Bakhmutsky, M. V., Oliver, M. S., Engelhardt, S. M., & Squibb, K. S. (2011). Measures of genotoxicity in Gulf war I veterans exposed to depleted uranium. Environmental and Molecular Mutagenesis, 52(7), 569-581. https://doi.org/10.1002/em.20658