Measurement of Spin-Lattice Relaxation Times in Systems Undergoing Chemical Exchange

A. Horska, J. Horsky, R. G S Spencer

Research output: Contribution to journalArticle

Abstract

A new method is presented for measuring spin-lattice relaxation times in systems with chemical exchange. The method is based on an analysis of the effect of exchange on saturation factors. Unlike the inversion-recovery method with saturation, our experiment does not require selective excitation; it also does not require a fit of data to a multiple-exponential model, in contrast to inversion recovery without saturation. A number of variations of the experiment are presented, which are applicable to different regimes of T1 and exchange-rate values. The methods are demonstrated for the creatine kinase reaction in an in vitro sample.

Original languageEnglish (US)
Pages (from-to)82-89
Number of pages8
JournalJournal of Magnetic Resonance, Series A
Volume110
Issue number1
DOIs
StatePublished - Sep 1994
Externally publishedYes

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Spin-lattice relaxation
spin-lattice relaxation
Relaxation time
relaxation time
saturation
Recovery
Creatine Kinase
recovery
creatine
inversions
Experiments
excitation

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Measurement of Spin-Lattice Relaxation Times in Systems Undergoing Chemical Exchange. / Horska, A.; Horsky, J.; Spencer, R. G S.

In: Journal of Magnetic Resonance, Series A, Vol. 110, No. 1, 09.1994, p. 82-89.

Research output: Contribution to journalArticle

Horska, A. ; Horsky, J. ; Spencer, R. G S. / Measurement of Spin-Lattice Relaxation Times in Systems Undergoing Chemical Exchange. In: Journal of Magnetic Resonance, Series A. 1994 ; Vol. 110, No. 1. pp. 82-89.
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