Partial flow volume curves (PEF(25%)) were measured daily in eight healthy young adults with experimental rhinovirus colds and in six non-infected controls. There were no differences in the changes in PEF(25%) values between infected and non-infected volunteers. The co-efficient of variation of the PEF(25%) in non-infected volunteers was 23%. We conclude that we were unable to detect airway obstruction in volunteers with experimental rhinovirus using the PEF(25%), a test with a high co-efficient of variation and, therefore, a low sensitivity for airway obstruction which may be reversed by a deep inhalation. Airway obstruction which was reversed by deep inhalation was not detected in either the infected or uninfected volunteers.
|Original language||English (US)|
|Number of pages||5|
|Issue number||SUPPL. 413|
|State||Published - Dec 1 1984|
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