Abstract
The purpose of the Advanced Multiple Projection Dual Energy X-ray Absorptiometry (AMPDXA) Scanning System project is to design, build, and test a precision scanner system for monitoring the deleterious effects of weightlessness on the human musculoskeletal system during prolonged spaceflight. The instrument uses dual energy x-ray absorptiometry (DXA) principles and is designed to measure bone mineral density (BMD), decompose soft tissue into fat and muscle, and derive structural properties (cross-sections, moments of inertia). Such data permits assessment of microgravity effects on bone and muscle and the associated fracture risk upon returning to planetary gravity levels. Multiple projections, coupled with axial translation, provide three-dimensional geometric properties suitable for accurate structural analysis. This structural analysis, coupled with bone models and estimated loads, defines the fracture risk. The scanner will be designed to minimize volume and mass (46-kg goal), while maintaining the required mechanical stability for high-precision measurement. The AMPDXA will be able to detect changes less than 1% in bone mass and geometry and changes less than 5% in muscle mass.
Original language | English (US) |
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Pages (from-to) | 2168-2169 |
Number of pages | 2 |
Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
Volume | 3 |
State | Published - Dec 1 2002 |
Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: Oct 23 2002 → Oct 26 2002 |
Keywords
- Bone mineral density
- Dual x-ray absorptiometry
- Microgravity-induced bone loss
- Osteoporosis
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics