Measles-associated diarrhea in hospitalized children in Lima, Peru: Pathogenic agents and impact on growth

B. L. Greenberg, R. B. Sack, E. Salazar-Lindo, E. Budge, M. Gutierrez, M. Campos, A. Visberg, R. Leon-Barna, A. Yi, D. Maurutia, M. Gomez, I. Lindo, E. Jaurequi

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29 Scopus citations


Because the causes of measles-associated diarrhea are not well known, 0- to 5-year-old children presenting to the hospital with measles-associated diarrhea (cases, n = 77) or acute diarrhea only (controls, n = 77) were compared. Growth and diarrheal morbidity were evaluated for 1 month after acute illness. Campylobacter jejuni was more frequently isolated from cases (31%) than controls (16%; P = .03). Rotavirus was absent in all cases versus 28% of controls (P <.001). Incidence density for new episodes of diarrhea was significantly greater in cases (6.5 vs. 4.1; odds ratio, 1.6; confidence intervals, 1.09-2.34; P = .01), as was duration of episodes (3 vs. 2 days, P = .02). Both groups showed similar positive cumulative percentage weight gains throughout follow-up. These data support the theory of measles as a risk factor for developing diarrhea. The bacteriologic and virologic findings may reflect the immunologic response of the host to measles infection.

Original languageEnglish (US)
Pages (from-to)495-502
Number of pages8
JournalJournal of Infectious Diseases
Issue number3
StatePublished - Mar 1991

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases


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