Mean transit time image -A new method of analyzing brain perfusion studies

Zsolt Szabó, Friedrich Ritzl

Research output: Contribution to journalArticlepeer-review

Abstract

Point-by-point calculation of the mean transit time based on gamma fit was used to analyze brain perfusion studies in a vertex view. The algorithm and preliminary results in normal brain and in different stages of cerebral perfusion abnormality (ischemia, stroke, migraine, tumor, abscess) are demonstrated. In contrast to the traditional methods using fixed, a priori defined regions of interest this type of mapping of the relative regional cerebral perfusion shows more clearly the irregular outlines of the disturbance. Right to left activity ratios in the arterial part of the time-activity curves showed significant correlation with the mean transit time ratios (Qt=1.185-0.192 Qan=38, r=0.716, P< 0.001).

Original languageEnglish (US)
Pages (from-to)201-205
Number of pages5
JournalEuropean Journal of Nuclear Medicine
Volume8
Issue number5
DOIs
StatePublished - May 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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