Abstract
Multiple sclerosis (MS) is a disease of the central nervous system in which immune mediated damage to myelin is characteristic. For an overview of this condition and its pathophysiology, please refer to one of many excellent published reviews (Sorensen and Ransohoff, 1998; Weiner, 2009). To follow, is a discussion focused on the possibility that synaptic injury occurs in at least a subset of patients, and that matrix metalloproteinases (MMPs) play a role in such.
Original language | English (US) |
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Article number | Article 130 |
Journal | Frontiers in Psychiatry |
Volume | 1 |
Issue number | OCT |
DOIs | |
State | Published - 2010 |
Externally published | Yes |
Keywords
- Adhesion molecule
- Cadherin
- Icam
- Matrix metalloproteinase
- Mmp
- Multiple sclerosis
- Synapse
ASJC Scopus subject areas
- Psychiatry and Mental health