Maternal serum alpha-fetoprotein screening after chorionic villus sampling

Mary E. Sigler, Claudia R. Colyer, Judith P. Rossiter, Andrew D. Dorfmann, Shirley L. Jones, Joseph D. Schulman

Research output: Contribution to journalArticle

Abstract

To evaluate whether maternal serum alpha-fetoprotein (MSAFP) concentrations at 15-18 weeks' gestation are influenced by chorionic villus sampling performed three to ten weeks earlier, MSAFP levels were determined for 417 postchorionic villus sampling patients and 967 control subjects without previous chorionic villus sampling. Statistical comparison of the medians, distributions, and proportions above defined multiples of the median demonstrated no significant difference between the two populations. These results indicate that MSAFP screening in postchorionic villus sampling patients should be reliable and that values may be interpreted using criteria similar to those used for the general population.

Original languageEnglish (US)
Pages (from-to)875-877
Number of pages3
JournalObstetrics and Gynecology
Volume70
Issue number6
StatePublished - 1987
Externally publishedYes

Fingerprint

Chorionic Villi Sampling
alpha-Fetoproteins
Mothers
Serum
Population
Pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Sigler, M. E., Colyer, C. R., Rossiter, J. P., Dorfmann, A. D., Jones, S. L., & Schulman, J. D. (1987). Maternal serum alpha-fetoprotein screening after chorionic villus sampling. Obstetrics and Gynecology, 70(6), 875-877.

Maternal serum alpha-fetoprotein screening after chorionic villus sampling. / Sigler, Mary E.; Colyer, Claudia R.; Rossiter, Judith P.; Dorfmann, Andrew D.; Jones, Shirley L.; Schulman, Joseph D.

In: Obstetrics and Gynecology, Vol. 70, No. 6, 1987, p. 875-877.

Research output: Contribution to journalArticle

Sigler, ME, Colyer, CR, Rossiter, JP, Dorfmann, AD, Jones, SL & Schulman, JD 1987, 'Maternal serum alpha-fetoprotein screening after chorionic villus sampling', Obstetrics and Gynecology, vol. 70, no. 6, pp. 875-877.
Sigler ME, Colyer CR, Rossiter JP, Dorfmann AD, Jones SL, Schulman JD. Maternal serum alpha-fetoprotein screening after chorionic villus sampling. Obstetrics and Gynecology. 1987;70(6):875-877.
Sigler, Mary E. ; Colyer, Claudia R. ; Rossiter, Judith P. ; Dorfmann, Andrew D. ; Jones, Shirley L. ; Schulman, Joseph D. / Maternal serum alpha-fetoprotein screening after chorionic villus sampling. In: Obstetrics and Gynecology. 1987 ; Vol. 70, No. 6. pp. 875-877.
@article{0040510a02be4d03b873c0253c50a8a5,
title = "Maternal serum alpha-fetoprotein screening after chorionic villus sampling",
abstract = "To evaluate whether maternal serum alpha-fetoprotein (MSAFP) concentrations at 15-18 weeks' gestation are influenced by chorionic villus sampling performed three to ten weeks earlier, MSAFP levels were determined for 417 postchorionic villus sampling patients and 967 control subjects without previous chorionic villus sampling. Statistical comparison of the medians, distributions, and proportions above defined multiples of the median demonstrated no significant difference between the two populations. These results indicate that MSAFP screening in postchorionic villus sampling patients should be reliable and that values may be interpreted using criteria similar to those used for the general population.",
author = "Sigler, {Mary E.} and Colyer, {Claudia R.} and Rossiter, {Judith P.} and Dorfmann, {Andrew D.} and Jones, {Shirley L.} and Schulman, {Joseph D.}",
year = "1987",
language = "English (US)",
volume = "70",
pages = "875--877",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Maternal serum alpha-fetoprotein screening after chorionic villus sampling

AU - Sigler, Mary E.

AU - Colyer, Claudia R.

AU - Rossiter, Judith P.

AU - Dorfmann, Andrew D.

AU - Jones, Shirley L.

AU - Schulman, Joseph D.

PY - 1987

Y1 - 1987

N2 - To evaluate whether maternal serum alpha-fetoprotein (MSAFP) concentrations at 15-18 weeks' gestation are influenced by chorionic villus sampling performed three to ten weeks earlier, MSAFP levels were determined for 417 postchorionic villus sampling patients and 967 control subjects without previous chorionic villus sampling. Statistical comparison of the medians, distributions, and proportions above defined multiples of the median demonstrated no significant difference between the two populations. These results indicate that MSAFP screening in postchorionic villus sampling patients should be reliable and that values may be interpreted using criteria similar to those used for the general population.

AB - To evaluate whether maternal serum alpha-fetoprotein (MSAFP) concentrations at 15-18 weeks' gestation are influenced by chorionic villus sampling performed three to ten weeks earlier, MSAFP levels were determined for 417 postchorionic villus sampling patients and 967 control subjects without previous chorionic villus sampling. Statistical comparison of the medians, distributions, and proportions above defined multiples of the median demonstrated no significant difference between the two populations. These results indicate that MSAFP screening in postchorionic villus sampling patients should be reliable and that values may be interpreted using criteria similar to those used for the general population.

UR - http://www.scopus.com/inward/record.url?scp=0023483268&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023483268&partnerID=8YFLogxK

M3 - Article

C2 - 2446224

AN - SCOPUS:0023483268

VL - 70

SP - 875

EP - 877

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 6

ER -