TY - JOUR
T1 - Maternal pemphigus vulgaris with in vivo bound antibodies in the stillborn fetus
AU - Green, David
AU - Maize, John C.
PY - 1982/1/1
Y1 - 1982/1/1
N2 - A 42-year-old black woman, gravida V, para IV, developed a recurrence of pemphigus vulgaris in the third trimester of pregnancy. She delivered a 2,056-gm stillborn female fetus in the seventh month, 2 days after ultrasonography had demonstrated absence of fetal cardiac activity and other evidence of intrauterine fetal death. The macerated fetus had peeling of its skin and an intact bulla on the foot. Fetal cardiac blood, obtained after delivery, showed the presence of pemphigus antibodies at a titer of 20. Direct immunofluorescence of fetal skin demonstrated IgG in the epidermal intercellular spaces. Autolytic changes of the skin, however, precluded definitive histologic documentation of acantholytic disease.
AB - A 42-year-old black woman, gravida V, para IV, developed a recurrence of pemphigus vulgaris in the third trimester of pregnancy. She delivered a 2,056-gm stillborn female fetus in the seventh month, 2 days after ultrasonography had demonstrated absence of fetal cardiac activity and other evidence of intrauterine fetal death. The macerated fetus had peeling of its skin and an intact bulla on the foot. Fetal cardiac blood, obtained after delivery, showed the presence of pemphigus antibodies at a titer of 20. Direct immunofluorescence of fetal skin demonstrated IgG in the epidermal intercellular spaces. Autolytic changes of the skin, however, precluded definitive histologic documentation of acantholytic disease.
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U2 - 10.1016/S0190-9622(82)70125-2
DO - 10.1016/S0190-9622(82)70125-2
M3 - Article
C2 - 6890077
AN - SCOPUS:0019948138
SN - 0190-9622
VL - 7
SP - 388
EP - 392
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 3
ER -