Maternal experience produces long-lasting behavioral modifications in the rat

Gennifer Love; Nicole Torrey; Ilan McNamara; Melissa Morgan; Margaret Banks; Naomi W. Hester; Erica R. Glasper; A. Courtney DeVries; Craig H. Kinsley; Kelly G. Lambert

doi:10.1037/0735-7044.119.4.1084

Maternal experience produces long-lasting behavioral modifications in the rat

Gennifer Love, Nicole Torrey, Ilan McNamara, Melissa Morgan, Margaret Banks, Naomi W. Hester, Erica R. Glasper, A. Courtney DeVries, Craig H. Kinsley, Kelly G. Lambert

Research output: Contribution to journal › Article › peer-review

110 Scopus citations

Abstract

From 5 to 22 months of age, cognitive and emotional responses of nulliparous, primiparous, and multiparous rats were assessed using a dry land maze (DLM) and an elevated plus-maze (EPM) at 4-month intervals. Parous rats exhibited improved spatial memory in the probe and competitive versions of the DLM, and more exploration in the EPM and a novel stimulus test relative to nulliparous females. The nulliparous females, however, outperformed parous rats during the DLM visual cue test at 17 months of age. At 23 months, no differences in stressed corticosterone levels or Golgi-stained hippocampal neurons were observed. Thus, cognitive and emotional modifications were observed in parous rats; the neurobiological mechanisms for these enduring effects, however, remain to be identified.

Original language	English (US)
Pages (from-to)	1084-1096
Number of pages	13
Journal	Behavioral Neuroscience
Volume	119
Issue number	4
DOIs	https://doi.org/10.1037/0735-7044.119.4.1084
State	Published - Aug 1 2005
Externally published	Yes

Keywords

Exploratory behavior
Hippocampus
Maternal behavior
Neuroplasticity
Spatial memory

ASJC Scopus subject areas

Behavioral Neuroscience

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10.1037/0735-7044.119.4.1084

Cite this

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title = "Maternal experience produces long-lasting behavioral modifications in the rat",

abstract = "From 5 to 22 months of age, cognitive and emotional responses of nulliparous, primiparous, and multiparous rats were assessed using a dry land maze (DLM) and an elevated plus-maze (EPM) at 4-month intervals. Parous rats exhibited improved spatial memory in the probe and competitive versions of the DLM, and more exploration in the EPM and a novel stimulus test relative to nulliparous females. The nulliparous females, however, outperformed parous rats during the DLM visual cue test at 17 months of age. At 23 months, no differences in stressed corticosterone levels or Golgi-stained hippocampal neurons were observed. Thus, cognitive and emotional modifications were observed in parous rats; the neurobiological mechanisms for these enduring effects, however, remain to be identified.",

keywords = "Exploratory behavior, Hippocampus, Maternal behavior, Neuroplasticity, Spatial memory",

author = "Gennifer Love and Nicole Torrey and Ilan McNamara and Melissa Morgan and Margaret Banks and Hester, {Naomi W.} and Glasper, {Erica R.} and DeVries, {A. Courtney} and Kinsley, {Craig H.} and Lambert, {Kelly G.}",

year = "2005",

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doi = "10.1037/0735-7044.119.4.1084",

language = "English (US)",

volume = "119",

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AU - Love, Gennifer

AU - Torrey, Nicole

AU - McNamara, Ilan

AU - Morgan, Melissa

AU - Banks, Margaret

AU - Hester, Naomi W.

AU - Glasper, Erica R.

AU - DeVries, A. Courtney

AU - Kinsley, Craig H.

AU - Lambert, Kelly G.

PY - 2005/8/1

Y1 - 2005/8/1

N2 - From 5 to 22 months of age, cognitive and emotional responses of nulliparous, primiparous, and multiparous rats were assessed using a dry land maze (DLM) and an elevated plus-maze (EPM) at 4-month intervals. Parous rats exhibited improved spatial memory in the probe and competitive versions of the DLM, and more exploration in the EPM and a novel stimulus test relative to nulliparous females. The nulliparous females, however, outperformed parous rats during the DLM visual cue test at 17 months of age. At 23 months, no differences in stressed corticosterone levels or Golgi-stained hippocampal neurons were observed. Thus, cognitive and emotional modifications were observed in parous rats; the neurobiological mechanisms for these enduring effects, however, remain to be identified.

AB - From 5 to 22 months of age, cognitive and emotional responses of nulliparous, primiparous, and multiparous rats were assessed using a dry land maze (DLM) and an elevated plus-maze (EPM) at 4-month intervals. Parous rats exhibited improved spatial memory in the probe and competitive versions of the DLM, and more exploration in the EPM and a novel stimulus test relative to nulliparous females. The nulliparous females, however, outperformed parous rats during the DLM visual cue test at 17 months of age. At 23 months, no differences in stressed corticosterone levels or Golgi-stained hippocampal neurons were observed. Thus, cognitive and emotional modifications were observed in parous rats; the neurobiological mechanisms for these enduring effects, however, remain to be identified.

KW - Exploratory behavior

KW - Hippocampus

KW - Maternal behavior

KW - Neuroplasticity

KW - Spatial memory

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Maternal experience produces long-lasting behavioral modifications in the rat

Abstract

Keywords

ASJC Scopus subject areas

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