Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood

H. Gonçalves, R. M. Pearson, B. L. Horta, D. A. González-Chica, E. Castilho, M. Damiani, R. C. Lima, D. P. Gigante, F. C. Barros, A. Stein, C. G. Victora

Research output: Contribution to journalArticle

Abstract

Background: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood. Method: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated. Results: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71–7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers. Conclusions: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.

Original languageEnglish (US)
JournalPsychological Medicine
DOIs
StateAccepted/In press - Oct 12 2015
Externally publishedYes

Fingerprint

Anxiety
Mothers
Depression
Nuclear Family
Brazil
Mental Health
Cohort Studies
Public Health
Parturition
Confidence Intervals
Population

Keywords

  • Cohort study
  • common mental disorder
  • intergenerational
  • mental health
  • offspring

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Applied Psychology

Cite this

Gonçalves, H., Pearson, R. M., Horta, B. L., González-Chica, D. A., Castilho, E., Damiani, M., ... Victora, C. G. (Accepted/In press). Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood. Psychological Medicine. https://doi.org/10.1017/S0033291715001956

Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood. / Gonçalves, H.; Pearson, R. M.; Horta, B. L.; González-Chica, D. A.; Castilho, E.; Damiani, M.; Lima, R. C.; Gigante, D. P.; Barros, F. C.; Stein, A.; Victora, C. G.

In: Psychological Medicine, 12.10.2015.

Research output: Contribution to journalArticle

Gonçalves, H, Pearson, RM, Horta, BL, González-Chica, DA, Castilho, E, Damiani, M, Lima, RC, Gigante, DP, Barros, FC, Stein, A & Victora, CG 2015, 'Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood', Psychological Medicine. https://doi.org/10.1017/S0033291715001956
Gonçalves, H. ; Pearson, R. M. ; Horta, B. L. ; González-Chica, D. A. ; Castilho, E. ; Damiani, M. ; Lima, R. C. ; Gigante, D. P. ; Barros, F. C. ; Stein, A. ; Victora, C. G. / Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood. In: Psychological Medicine. 2015.
@article{aeca41d09aee4d2aa1f9d49d6f0de1a5,
title = "Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood",
abstract = "Background: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood. Method: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated. Results: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95{\%} confidence interval 2.71–7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers. Conclusions: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.",
keywords = "Cohort study, common mental disorder, intergenerational, mental health, offspring",
author = "H. Gon{\cc}alves and Pearson, {R. M.} and Horta, {B. L.} and Gonz{\'a}lez-Chica, {D. A.} and E. Castilho and M. Damiani and Lima, {R. C.} and Gigante, {D. P.} and Barros, {F. C.} and A. Stein and Victora, {C. G.}",
year = "2015",
month = "10",
day = "12",
doi = "10.1017/S0033291715001956",
language = "English (US)",
journal = "Psychological Medicine",
issn = "0033-2917",
publisher = "Cambridge University Press",

}

TY - JOUR

T1 - Maternal depression and anxiety predicts the pattern of offspring symptoms during their transition to adulthood

AU - Gonçalves, H.

AU - Pearson, R. M.

AU - Horta, B. L.

AU - González-Chica, D. A.

AU - Castilho, E.

AU - Damiani, M.

AU - Lima, R. C.

AU - Gigante, D. P.

AU - Barros, F. C.

AU - Stein, A.

AU - Victora, C. G.

PY - 2015/10/12

Y1 - 2015/10/12

N2 - Background: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood. Method: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated. Results: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71–7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers. Conclusions: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.

AB - Background: Episodes of depression and anxiety (D&A) during the transition from late adolescence to adulthood, particularly when persistent, are predictive of long-term disorders and associated public health burden. Understanding risk factors at this time is important to guide intervention. The current objective was to investigate the associations between maternal symptoms of D&A with offspring symptoms during their transition to adulthood. Method: Data from a large population-based birth cohort study, in South Brazil, were used. Prospective associations between maternal D&A and offspring risk of these symptoms during the transition to adulthood (18/19, 24 and 30 years) were estimated. Results: Maternal D&A in adolescence was associated with offspring symptoms across the transition to adulthood, associations were consistently stronger for females than for males. Daughters whose mothers reported D&A were 4.6 times (95% confidence interval 2.71–7.84) as likely to report D&A at all three time-points, than daughters of symptom-free mothers. Conclusions: Maternal D&A is associated with persistent D&A during the daughter's transition to adulthood. Intervention strategies should consider the mother's mental health.

KW - Cohort study

KW - common mental disorder

KW - intergenerational

KW - mental health

KW - offspring

UR - http://www.scopus.com/inward/record.url?scp=84943788820&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84943788820&partnerID=8YFLogxK

U2 - 10.1017/S0033291715001956

DO - 10.1017/S0033291715001956

M3 - Article

C2 - 26456404

AN - SCOPUS:84943788820

JO - Psychological Medicine

JF - Psychological Medicine

SN - 0033-2917

ER -