Maternal and neonatal colonization in Bangladesh: Prevalences, etiologies and risk factors

G. J. Chan, J. K. Modak, A. A. Mahmud, A. H. Baqui, R. E. Black, S. K. Saha

Research output: Contribution to journalArticlepeer-review

Abstract

Objective:To estimate the prevalence of maternal colonizers in South Asia and their potential to colonize the umbilicus, an important precondition causing neonatal sepsis.Study design:We conducted a cross-sectional study at a maternity center in Dhaka with 1219 pregnant women and a subset of 152 newborns from 15 January to 31 October 2011. During labor, study paramedics collected vaginal swabs for bacterial culture and rectal swabs for Group B Streptococcus (GBS) testing. Community health workers collected neonatal umbilical swabs. Log-binomial regression models were used to estimate risk ratios.Result:In all, 454 women (37.2%, 95% confidence interval (CI) 34.5 to 40.0%) were colonized. The most common organisms isolated were Staphylococcus aureus, Non-GBS and GBS. A total of 94 women (7.7%, 95% CI 6.2 to 9.2%) were colonized with GBS. The risk of GBS umbilical colonization was higher (RR=12.98, 95% CI 3.97 to 42.64) among newborns of mothers with GBS colonization.Conclusion:Newborns of mothers colonized with GBS are at higher risk of developing umbilical colonization.

Original languageEnglish (US)
Pages (from-to)971-976
Number of pages6
JournalJournal of Perinatology
Volume33
Issue number12
DOIs
StatePublished - Dec 1 2013

Keywords

  • Bangladesh
  • etiologies
  • maternal and neonatal colonization
  • risk factors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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