Mass spectrometry for genotyping: An emerging tool for molecular medicine

Peta E. Jackson, Peter F. Scholl, John D. Groopman

Research output: Contribution to journalReview articlepeer-review

Abstract

Recent technological innovations have made proteins and nucleic acids accessible to mass spectrometric analysis. As a result of their inherently high specificity, accuracy and throughput, there is considerable interest in developing mass spectrometric methods for genotype analysis in clinical diagnostic and research applications. This review outlines some of the most promising genotyping methods developed using electrospray and matrix-assisted laser-desorption-ionization mass spectrometry.

Original languageEnglish (US)
Pages (from-to)271-276
Number of pages6
JournalMolecular Medicine
Volume6
Issue number7
DOIs
StatePublished - Jul 2000

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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