Mass spectrometric analysis of proteins

Catherine Fenselau, Martha M. Vestling, Robert J. Cotter

Research output: Contribution to journalArticle

Abstract

The past year has seen greatly increased acceptance and application of the analytical capabilities of mass spectrometry by the biochemical community. The technique has been used to provide accurate mass determinations of non-covalently bound protein complexes, rapid mapping of molecular weights of altered peptides in protease digests, sequencing by collisional activation in tandem mass spectrometry, characterization of glycosylation and other modifications, and quantitation of peptides used in clinical diagnostics.

Original languageEnglish (US)
Pages (from-to)14-19
Number of pages6
JournalCurrent Opinion in Biotechnology
Volume4
Issue number1
DOIs
StatePublished - Feb 1993

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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