Mass spectral analysis of murine epidermal growth factor

Karen J. Hyver, Joseph E. Campana, Robert J. Cotter, Catherine Fenselau

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Fast atom bombardment mass spectrometry has been used to characterize epidermal growth factor isolated from mouse submaxillary glands. The preparation is found to consist of two peptides, one of which has the average molecular weight predicted for the familiar gene product. The molecular weight of the second component is found to be reduced by the mass of one asparagine residue. These observations are discussed in light of previous reports of heterogeneity.

Original languageEnglish (US)
Pages (from-to)1287-1293
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number3
StatePublished - Aug 15 1985

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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