Mass spectral analysis of complex lipids desorbed directly from lyophilized membranes and cells

D. N. Heller, C. Fenselau, R. J. Cotter, P. Demirev, J. K. Olthoff, J. Honovich, M. Uy, T. Tanaka, Y. Kishimoto

Research output: Contribution to journalArticle

Abstract

Three desorption ionization techniques - laser desorption, plasma desorption and fast atom bombardment mass spectrometry - have been applied to lyophilized cells, membranes, lysed cells and various extracts. It has been shown that intact polar lipids are selectively desorbed from biological membranes by these methods and that their mass spectra provide "fingerprints" which reflect the unique biochemical composition of each class of cell or membrane.

Original languageEnglish (US)
Pages (from-to)194-199
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume142
Issue number1
DOIs
StatePublished - Jan 15 1987

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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  • Cite this

    Heller, D. N., Fenselau, C., Cotter, R. J., Demirev, P., Olthoff, J. K., Honovich, J., Uy, M., Tanaka, T., & Kishimoto, Y. (1987). Mass spectral analysis of complex lipids desorbed directly from lyophilized membranes and cells. Biochemical and Biophysical Research Communications, 142(1), 194-199. https://doi.org/10.1016/0006-291X(87)90470-0