Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial

Travis C. Porco; John Hart; Ahmed M. Arzika; Jerusha Weaver; Khumbo Kalua; Zakayo Mrango; Sun Y. Cotter; Nicole E. Stoller; Kieran S. O'Brien; Dionna M. Fry; Benjamin Vanderschelden; Catherine E. Oldenburg; Sheila K. West; Robin L. Bailey; Jeremy D. Keenan; Thomas M. Lietman

doi:10.1093/cid/ciy973

Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial

Travis C. Porco, John Hart, Ahmed M. Arzika, Jerusha Weaver, Khumbo Kalua, Zakayo Mrango, Sun Y. Cotter, Nicole E. Stoller, Kieran S. O'Brien, Dionna M. Fry, Benjamin Vanderschelden, Catherine E. Oldenburg, Sheila K. West, Robin L. Bailey, Jeremy D. Keenan, Thomas M. Lietman

School of Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

In a large community-randomized trial, biannual azithromycin distributions significantly reduced postneonatal childhood mortality in sub-Saharan African sites. Here, we present a prespecified secondary analysis showing that much of the protective effect was in the first 3 months postdistribution. Distributing more frequently than biannually could be considered if logistically feasible. Clinical Trials Registration. NCT02047981.

Original language	English (US)
Article number	ciy973
Pages (from-to)	2114-2116
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	68
Issue number	12
DOIs	https://doi.org/10.1093/cid/ciy973
State	Published - Jun 2019

Keywords

azithromycin
childhood mortality
sub-Saharan Africa

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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Porco, T. C., Hart, J., Arzika, A. M., Weaver, J., Kalua, K., Mrango, Z., Cotter, S. Y., Stoller, N. E., O'Brien, K. S., Fry, D. M., Vanderschelden, B., Oldenburg, C. E., West, S. K., Bailey, R. L., Keenan, J. D., & Lietman, T. M. (2019). Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial. Clinical Infectious Diseases, 68(12), 2114-2116. Article ciy973. https://doi.org/10.1093/cid/ciy973

Porco, TC, Hart, J, Arzika, AM, Weaver, J, Kalua, K, Mrango, Z, Cotter, SY, Stoller, NE, O'Brien, KS, Fry, DM, Vanderschelden, B, Oldenburg, CE, West, SK, Bailey, RL, Keenan, JD & Lietman, TM 2019, 'Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial', Clinical Infectious Diseases, vol. 68, no. 12, ciy973, pp. 2114-2116. https://doi.org/10.1093/cid/ciy973

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Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial

Abstract

Keywords

ASJC Scopus subject areas

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