Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial

Travis C. Porco, John Hart, Ahmed M. Arzika, Jerusha Weaver, Khumbo Kalua, Zakayo Mrango, Sun Y. Cotter, Nicole E. Stoller, Kieran S. O'Brien, Dionna M. Fry, Benjamin Vanderschelden, Catherine E. Oldenburg, Sheila K. West, Robin L. Bailey, Jeremy D. Keenan, Thomas M. Lietman

Research output: Contribution to journalArticlepeer-review

Abstract

In a large community-randomized trial, biannual azithromycin distributions significantly reduced postneonatal childhood mortality in sub-Saharan African sites. Here, we present a prespecified secondary analysis showing that much of the protective effect was in the first 3 months postdistribution. Distributing more frequently than biannually could be considered if logistically feasible. Clinical Trials Registration. NCT02047981.

Original languageEnglish (US)
Article numberciy973
Pages (from-to)2114-2116
Number of pages3
JournalClinical Infectious Diseases
Volume68
Issue number12
DOIs
StatePublished - Jun 2019

Keywords

  • azithromycin
  • childhood mortality
  • sub-Saharan Africa

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Mass Oral Azithromycin for Childhood Mortality: Timing of Death after Distribution in the MORDOR Trial'. Together they form a unique fingerprint.

Cite this