A case is presented of a 26-year-old man, with no previous psychiatric history, who had an acute psychosis after smoking less than two marihuana cigarettes. The patient's own verbatim account of his psychosis is reported. The same patient also has a history of pathological reactions to alcohol. Personality factors in the patient, which help to account for his drug reactions are discussed. Factors influencing a subject's reaction to marihuana are described as including personality factors, the set and the setting. The pharmacological actions of the drug and the dosage interact with the above factors. The same statements can be made with regard to other centrally active drugs. The implications of this case, which illustrates many important points, are reviewed.
ASJC Scopus subject areas
- Psychiatry and Mental health