Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Hendrik P.N. Scholl, Andreas M. Schuster, Reinhard Vonthein, Eberhart Zrenner

Research output: Contribution to journalArticle

Abstract

In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.

Original languageEnglish (US)
Pages (from-to)1053-1061
Number of pages9
JournalVision Research
Volume42
Issue number8
DOIs
StatePublished - Apr 13 2002

Keywords

  • Best
  • Dystrophy
  • Electroretinogram (ERG)
  • Maculopathy
  • Multifocal

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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