Management strategies for pyoderma gangrenosum: Case studies and review of literature

Shai M. Rozen, Maurice Y. Nahabedian, Paul Manson

Research output: Contribution to journalArticle

Abstract

Pyoderma gangrenosum (PG) is a systemic disease with cutaneous manifestations consisting of necrotizing ulceration. The etiology of PG is controversial, and optimal management strategies have not been established. Current management is primarily medical to control the systemic inflammatory process, with occasional surgical intervention at the ulcer site. Based on the current literature and on the authors' clinical experience, the optimal outcome depends on early diagnoses and a combination of medical and surgical therapy. Initial management is directed toward medical control of the inflammatory process and local wound care. Surgical strategies involve recipient site preparation via local wound care and serial allograft followed by autologous skin graft or muscle flap coverage when necessary. Long-term wound stabilization is obtained only through control of the systemic and local inflammatory process.

Original languageEnglish (US)
Pages (from-to)310-315
Number of pages6
JournalAnnals of Plastic Surgery
Volume47
Issue number3
StatePublished - 2001

Fingerprint

Pyoderma Gangrenosum
Wounds and Injuries
Skin Manifestations
Ulcer
Allografts
Early Diagnosis
Transplants
Muscles
Skin
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Management strategies for pyoderma gangrenosum : Case studies and review of literature. / Rozen, Shai M.; Nahabedian, Maurice Y.; Manson, Paul.

In: Annals of Plastic Surgery, Vol. 47, No. 3, 2001, p. 310-315.

Research output: Contribution to journalArticle

Rozen, Shai M. ; Nahabedian, Maurice Y. ; Manson, Paul. / Management strategies for pyoderma gangrenosum : Case studies and review of literature. In: Annals of Plastic Surgery. 2001 ; Vol. 47, No. 3. pp. 310-315.
@article{3f96e1306dac4b50a9ec158ae67e4c83,
title = "Management strategies for pyoderma gangrenosum: Case studies and review of literature",
abstract = "Pyoderma gangrenosum (PG) is a systemic disease with cutaneous manifestations consisting of necrotizing ulceration. The etiology of PG is controversial, and optimal management strategies have not been established. Current management is primarily medical to control the systemic inflammatory process, with occasional surgical intervention at the ulcer site. Based on the current literature and on the authors' clinical experience, the optimal outcome depends on early diagnoses and a combination of medical and surgical therapy. Initial management is directed toward medical control of the inflammatory process and local wound care. Surgical strategies involve recipient site preparation via local wound care and serial allograft followed by autologous skin graft or muscle flap coverage when necessary. Long-term wound stabilization is obtained only through control of the systemic and local inflammatory process.",
author = "Rozen, {Shai M.} and Nahabedian, {Maurice Y.} and Paul Manson",
year = "2001",
language = "English (US)",
volume = "47",
pages = "310--315",
journal = "Annals of Plastic Surgery",
issn = "0148-7043",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Management strategies for pyoderma gangrenosum

T2 - Case studies and review of literature

AU - Rozen, Shai M.

AU - Nahabedian, Maurice Y.

AU - Manson, Paul

PY - 2001

Y1 - 2001

N2 - Pyoderma gangrenosum (PG) is a systemic disease with cutaneous manifestations consisting of necrotizing ulceration. The etiology of PG is controversial, and optimal management strategies have not been established. Current management is primarily medical to control the systemic inflammatory process, with occasional surgical intervention at the ulcer site. Based on the current literature and on the authors' clinical experience, the optimal outcome depends on early diagnoses and a combination of medical and surgical therapy. Initial management is directed toward medical control of the inflammatory process and local wound care. Surgical strategies involve recipient site preparation via local wound care and serial allograft followed by autologous skin graft or muscle flap coverage when necessary. Long-term wound stabilization is obtained only through control of the systemic and local inflammatory process.

AB - Pyoderma gangrenosum (PG) is a systemic disease with cutaneous manifestations consisting of necrotizing ulceration. The etiology of PG is controversial, and optimal management strategies have not been established. Current management is primarily medical to control the systemic inflammatory process, with occasional surgical intervention at the ulcer site. Based on the current literature and on the authors' clinical experience, the optimal outcome depends on early diagnoses and a combination of medical and surgical therapy. Initial management is directed toward medical control of the inflammatory process and local wound care. Surgical strategies involve recipient site preparation via local wound care and serial allograft followed by autologous skin graft or muscle flap coverage when necessary. Long-term wound stabilization is obtained only through control of the systemic and local inflammatory process.

UR - http://www.scopus.com/inward/record.url?scp=0034855233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034855233&partnerID=8YFLogxK

M3 - Article

C2 - 11562037

AN - SCOPUS:0034855233

VL - 47

SP - 310

EP - 315

JO - Annals of Plastic Surgery

JF - Annals of Plastic Surgery

SN - 0148-7043

IS - 3

ER -