Management of severe Raynaud's phenomenon

Research output: Contribution to journalArticle

Abstract

Severe Raynaud's phenomenon is manifested by recurrent painful attacks often associated with digital ulcers, ischemic demarcation and amputation. Usually, a secondary disease process can be defined as a cause of severe Raynaud's phenomenon. Principles of management include treating the events as a medical emergency, carefully diagnosing and treating the underlying cause and instituting both nondrug and drug treatment early, before ischemic tissue damage occurs. Calcium channel blockers are currently the most effective oral vasodilator therapy for Raynaud's phenomenon. In some refractory cases, digital sympathectomy, fibrinolytic therapy, or infusion of prostanoids have been used with success. Understanding the complex pathogenesis of severe Raynaud's phenomenon will lead to new approaches to management in the future.

Original languageEnglish (US)
Pages (from-to)103-111
Number of pages9
JournalJournal of Clinical Rheumatology
Volume2
Issue number2
StatePublished - Apr 1996

Fingerprint

Raynaud Disease
Sympathectomy
Thrombolytic Therapy
Calcium Channel Blockers
Vasodilator Agents
Amputation
Ulcer
Prostaglandins
Emergencies
Therapeutics
Pharmaceutical Preparations

Keywords

  • Calcium channel blockers
  • Prostaglandins
  • Raynaud's phenomenon
  • Sympathectomy

ASJC Scopus subject areas

  • Rheumatology

Cite this

Management of severe Raynaud's phenomenon. / Wigley, Fredrick.

In: Journal of Clinical Rheumatology, Vol. 2, No. 2, 04.1996, p. 103-111.

Research output: Contribution to journalArticle

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