Management of Recurrent Malignant Salivary Neoplasms

Mazin Merdad, Jeremy D. Richmon, Harry Quon

Research output: Contribution to journalArticle

Abstract

The management of malignant salivary gland neoplasms is based on a surgical paradigm, with intraoperative findings and pathology guiding the role of local-regional adjuvant therapy. Despite high rates of local control, local relapse can be a dominant pattern of recurrence, presenting therapeutic challenges. Although an optimal management approach has not been established, aggressive salvage surgery is favored given the morbidity associated with tumor progression at the skull base and the lack of significant response associated with other available treatment modalities. Postoperative radiotherapy has been demonstrated to be effective in the initial management of malignant salivary gland neoplasms and is generally favored for recurrent, surgically resectable tumors for the appropriate patient.

Original languageEnglish (US)
Pages (from-to)168-174
Number of pages7
JournalAdvances in Oto-Rhino-Laryngology
Volume78
DOIs
StatePublished - 2016
Externally publishedYes

Fingerprint

Salivary Gland Neoplasms
Recurrence
Neoplasms
Skull Base
Radiotherapy
Therapeutics
Pathology
Morbidity

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Management of Recurrent Malignant Salivary Neoplasms. / Merdad, Mazin; Richmon, Jeremy D.; Quon, Harry.

In: Advances in Oto-Rhino-Laryngology, Vol. 78, 2016, p. 168-174.

Research output: Contribution to journalArticle

Merdad, Mazin ; Richmon, Jeremy D. ; Quon, Harry. / Management of Recurrent Malignant Salivary Neoplasms. In: Advances in Oto-Rhino-Laryngology. 2016 ; Vol. 78. pp. 168-174.
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