Management of recurrent hepatitis C in orthotopic liver transplant recipients

Geeta S. Karnik; Kirti Shetty

doi:10.1016/j.idc.2013.02.003

Management of recurrent hepatitis C in orthotopic liver transplant recipients

Geeta S. Karnik, Kirti Shetty

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

End-stage liver disease and hepatocellular carcinoma from chronic hepatitis C are the most common indications for orthotopic liver transplantation and the incidence of both are projected to increase over the next decade. Recurrent hepatitis C virus infection of the allograft is associated with an accelerated progression to cirrhosis, graft loss, and death. This article presents an overview of the natural history of hepatitis C virus recurrence in liver transplant recipients and guidance on optimal management strategies.

Original language	English (US)
Pages (from-to)	285-304
Number of pages	20
Journal	Infectious disease clinics of North America
Volume	27
Issue number	2
DOIs	https://doi.org/10.1016/j.idc.2013.02.003
State	Published - Jun 2013
Externally published	Yes

Keywords

Direct-acting antivirals
Hepatitis C virus
Immunosuppression
Liver transplant
Recurrence

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.idc.2013.02.003

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title = "Management of recurrent hepatitis C in orthotopic liver transplant recipients",

abstract = "End-stage liver disease and hepatocellular carcinoma from chronic hepatitis C are the most common indications for orthotopic liver transplantation and the incidence of both are projected to increase over the next decade. Recurrent hepatitis C virus infection of the allograft is associated with an accelerated progression to cirrhosis, graft loss, and death. This article presents an overview of the natural history of hepatitis C virus recurrence in liver transplant recipients and guidance on optimal management strategies.",

keywords = "Direct-acting antivirals, Hepatitis C virus, Immunosuppression, Liver transplant, Recurrence",

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AU - Karnik, Geeta S.

AU - Shetty, Kirti

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N2 - End-stage liver disease and hepatocellular carcinoma from chronic hepatitis C are the most common indications for orthotopic liver transplantation and the incidence of both are projected to increase over the next decade. Recurrent hepatitis C virus infection of the allograft is associated with an accelerated progression to cirrhosis, graft loss, and death. This article presents an overview of the natural history of hepatitis C virus recurrence in liver transplant recipients and guidance on optimal management strategies.

AB - End-stage liver disease and hepatocellular carcinoma from chronic hepatitis C are the most common indications for orthotopic liver transplantation and the incidence of both are projected to increase over the next decade. Recurrent hepatitis C virus infection of the allograft is associated with an accelerated progression to cirrhosis, graft loss, and death. This article presents an overview of the natural history of hepatitis C virus recurrence in liver transplant recipients and guidance on optimal management strategies.

KW - Direct-acting antivirals

KW - Hepatitis C virus

KW - Immunosuppression

KW - Liver transplant

KW - Recurrence

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JO - Infectious disease clinics of North America

JF - Infectious disease clinics of North America

IS - 2

ER -

Management of recurrent hepatitis C in orthotopic liver transplant recipients

Abstract

Keywords

ASJC Scopus subject areas

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