Management of Rare Breast Tumors and Male Breast Cancer

Research output: Contribution to journalArticle

Abstract

Purpose of Review: There is very little clinical trial data available to guide the management of uncommon breast cancers. This review draws on classic and recent retrospective data to synthesize a clearer understanding of the biology and behavior of these rare tumors. Recent Findings: Avoid disfiguring surgery in the pursuit of very wide margins for benign phyllodes tumors unless there are adverse histological features. Encapsulated papillary carcinoma is very good prognosis breast cancer; do not over treat. Metaplastic carcinoma is a basal type breast cancer that may be more responsive to “BRCA1-like” treatments. Complete excision of the capsule is curative for most implant-associated anaplastic large cell lymphomas. Aromatase inhibitors are still controversial for male breast cancer; tamoxifen is standard. Summary: Available data are useful for guiding the treatment of rare breast cancers, but it must be recognized that there is still a great deal to be learned about each of these entities.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalCurrent Breast Cancer Reports
DOIs
Publication statusAccepted/In press - Apr 11 2017

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Keywords

  • Breast neoplasms
  • Encapsulated papillary carcinoma
  • Implant-associated anaplastic large cell lymphoma
  • Male breast cancer
  • Metaplastic breast cancer
  • Neuroendocrine differentiation
  • Phyllodes tumor
  • Radiation-associated angiosarcoma

ASJC Scopus subject areas

  • Oncology

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