Management of radiation proctitis

Ankit Sarin, Bashar Safar

Research output: Contribution to journalReview article

Abstract

Radiation damage to the rectum following radiotherapy for pelvic malignancies can range from acute dose-limiting side effects to major morbidity affecting health-related quality of life. No standard guidelines exist for diagnosis and management of radiation proctitis. This article reviews the definitions, staging, and clinical features of radiation proctitis, and summarizes the modalities available for the treatment of acute and chronic radiation proctitis. Because of the paucity of well-controlled, blinded, randomized studies, it is not possible to fully assess the comparative efficacy of the different approaches to management. However, the evidence and rationale for use of the different strategies are presented.

Original languageEnglish (US)
Pages (from-to)913-925
Number of pages13
JournalGastroenterology Clinics of North America
Volume42
Issue number4
DOIs
StatePublished - Dec 1 2013

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Keywords

  • Argon plasma coagulation
  • Endoscopic laser therapy
  • Formalin
  • Hyperbaric oxygen
  • Radiation colitis
  • Radiation proctitis
  • Short-chain fatty acids
  • Sucralfate

ASJC Scopus subject areas

  • Gastroenterology

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