Management of intrathecal catheter-tip inflammatory masses: An updated 2007 consensus statement from an expert panel

Timothy Deer, Elliot S. Krames, Samuel Hassenbusch, Allen Burton, David Caraway, Stuart Dupen, James Eisenach, Michael Erdek, Eric Grigsby, Phillip Kim, Robert Levy, Gladstone McDowell, Nagy Mekhail, Sunil Panchal, Joshua Prager, Richard Rauck, Michael Saulino, Todd Sitzman, Peter Staats, Michael Stanton-HicksLisa Stearns, K. Dean Willis, William Witt, Kenneth Follett, Mark Huntoon, Leong Liem, James Rathmell, Mark Wallace, Eric Buchser, Michael Cousins, Ann Ver Donck

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Background. Expert panel of physicians and nonphysicians, all expert in intrathecal (IT) therapies, convened in the years 2000 and 2003 to make recommendations for the rational use of IT analgesics based on the preclinical and clinical literature known up to those times, presentations of the expert panel, discussions on current practice and standards, and the result of surveys of physicians using IT agents. An expert panel of physicians and convened in 2007 to review previous recommendations and to form recommendations for the rational use of IT agents as they pertain to new scientific and clinical information regarding the etiology, prevention and treatment for IT granuloma. Method. A review of preclinical and clinical literature from 2000 to 2006 was undertaken and disseminated to an expert panel of physicians. Focused discussions concerning the rational use of IT agents and its relationship to the etiology of, prevention of, and treatment of IT granuloma were held. Results. This report presents here new knowledge of the etiology of catheter tip granuloma and guidelines for its prevention and treatment.

Original languageEnglish (US)
Pages (from-to)77-91
Number of pages15
Issue number2
StatePublished - Apr 2008
Externally publishedYes


  • Complications
  • Etiology
  • Granuloma formation
  • Intrathecal
  • Nonopioids
  • Opioids
  • Prevention
  • Treatment

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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